New Therapeutics Targeting Colon Cancer Stem Cells (Q33639180)

28 July 2017

title

New Therapeutics Targeting Colon Cancer Stem Cells (English)

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28 July 2017

main subject

neoplastic stem cells

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1 reference

Arun Thenappan

1

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28 July 2017

Ying Li

2

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28 July 2017

Kirti Shetty

3

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28 July 2017

Lynt Johnson

4

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28 July 2017

E P Reddy

5

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28 July 2017

Lopa Mishra

6

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28 July 2017

publication date

1 October 2009

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Current colorectal cancer reports

28 July 2017

published in

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28 July 2017

volume

5

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28 July 2017

issue

4

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28 July 2017

page(s)

209

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Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition

28 July 2017

cites work

1 reference

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21 June 2018

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Colon cancer stem cells: implications for prevention and therapy

21 June 2018

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Calcium, calcium-sensing receptor and colon cancer

21 June 2018

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Human colon cancer stem cells: a new paradigm in gastrointestinal oncology

21 June 2018

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Crucial role of interleukin-4 in the survival of colon cancer stem cells

21 June 2018

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CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors

21 June 2018

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Colonic crypt organization and tumorigenesis

21 June 2018

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Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

21 June 2018

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Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice

21 June 2018

1 reference

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Identification of stem cells in small intestine and colon by marker gene Lgr5

21 June 2018

1 reference

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Biological and genetic characteristics of tumor-initiating cells in colon cancer

21 June 2018

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TGF-beta signaling alterations and susceptibility to colorectal cancer

21 June 2018

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Phenotypic characterization of human colorectal cancer stem cells

21 June 2018

1 reference

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Symmetric division of cancer stem cells--a key mechanism in tumor growth that should be targeted in future therapeutic approaches

21 June 2018

1 reference

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Identification of pancreatic cancer stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 June 2018

1 reference

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Identification and expansion of human colon-cancer-initiating cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.

21 June 2018

1 reference

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Targeting of CD44 eradicates human acute myeloid leukemic stem cells

21 June 2018

1 reference

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Colorectal cancer: genetics of development and metastasis

21 June 2018

1 reference

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Normal stem cells and cancer stem cells: the niche matters

21 June 2018

1 reference

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Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

21 June 2018

1 reference

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Prospective identification of tumorigenic prostate cancer stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Isolation and characterization of a putative intestinal stem cell fraction from mouse jejunum

21 June 2018

1 reference

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Wnt and calcium signaling: beta-catenin-independent pathways

21 June 2018

1 reference

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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Wnt signalling in stem cells and cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Cancer stem cells in nervous system tumors

21 June 2018

1 reference

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Tumor suppressor gene E-cadherin and its role in normal and malignant cells

21 June 2018

1 reference

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Expression of Musashi-1 in human normal colon crypt cells: a possible stem cell marker of human colon epithelium

21 June 2018

1 reference

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Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Prospective identification of tumorigenic breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

21 June 2018

Cancer statistics, 2001

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

TGFbeta signaling in growth control, cancer, and heritable disorders

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Transforming growth factor beta stimulation of colorectal cancer cell lines: type II receptor bypass and changes in adhesion molecule expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Identification of c-MYC as a target of the APC pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Lessons from hereditary colorectal cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Genetic alterations during colorectal-tumor development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Differential sensitivity of subclasses of human colon carcinoma cell lines to the growth inhibitory effects of transforming growth factor-beta 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Regulation of intestinal epithelial cell growth by transforming growth factor type beta

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Clonal origin of columnar, mucous, and endocrine cell lineages in human colorectal epithelium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

A genetic model for colorectal tumorigenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

How dysregulated colonic crypt dynamics cause stem cell overpopulation and initiate colon cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Expression pattern of Wnt signaling components in the adult intestine.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Transforming growth factor-beta suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818736

Transforming growth factor-beta signaling in stem cells and cancer

30 October 2018

1 reference

12 December 2020

EphB receptors coordinate migration and proliferation in the intestinal stem cell niche

1 reference

12 December 2020

Smad4 haploinsufficiency in mouse models for intestinal cancer

1 reference

12 December 2020

Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission

1 reference

12 December 2020

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

1 reference

12 December 2020

10.1007/S11888-009-0029-2

Identifiers

DOI

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28 July 2017

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28 July 2017

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