Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization (Q33641630)

28 July 2017

title

Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization (English)

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28 July 2017

Eleonora Grandi

5

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Donald M. Bers

object named as

Donald M Bers

8

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author name string

Lin Wu

1

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28 July 2017

Jihua Ma

2

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28 July 2017

Hong Li

3

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28 July 2017

Chao Wang

4

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28 July 2017

Peihua Zhang

6

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28 July 2017

Antao Luo

7

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28 July 2017

John C Shryock

9

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28 July 2017

Luiz Belardinelli

10

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28 July 2017

language of work or name

English

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publication date

11 April 2011

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28 July 2017

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28 July 2017

volume

123

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28 July 2017

issue

16

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28 July 2017

page(s)

1713-1720

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A novel computational model of the human ventricular action potential and Ca transient

28 July 2017

cites work

1 reference

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21 June 2018

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Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na(+) current in the heart

21 June 2018

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Self-augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency

21 June 2018

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Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine

21 June 2018

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21 June 2018

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Role of activated CaMKII in abnormal calcium homeostasis and I(Na) remodeling after myocardial infarction: insights from mathematical modeling

21 June 2018

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Use and abuse of QT and TRIaD in cardiac safety research: importance of study design and conduct

21 June 2018

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Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.

21 June 2018

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Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials

21 June 2018

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21 June 2018

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A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.

21 June 2018

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Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

21 June 2018

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Intracellular Ca(2+) concentration and rate adaptation of the cardiac action potential

21 June 2018

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The electrical restitution curve revisited: steep or flat slope--which is better?

21 June 2018

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Rate-dependent QT shortening mechanism for the LQT3 deltaKPQ mutant

21 June 2018

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Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential

21 June 2018

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Rate dependence of the effect of antiarrhythmic drugs delaying cardiac repolarization: an overview

21 June 2018

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Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

21 June 2018

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I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.

21 June 2018

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Reverse rate dependency is an intrinsic property of canine cardiac preparations.

30 October 2018

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Milrinone inhibits hypoxia or hydrogen dioxide-induced persistent sodium current in ventricular myocytes.

30 October 2018

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Frequency-dependent effects of various IKr blockers on cardiac action potential duration in a human atrial model.

30 October 2018

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An increase in late sodium current potentiates the proarrhythmic activities of low-risk QT-prolonging drugs in female rabbit hearts

30 October 2018

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Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes

30 October 2018

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Density and kinetics of I(Kr) and I(Ks) in guinea pig and rabbit ventricular myocytes explain different efficacy of I(Ks) blockade at high heart rate in guinea pig and rabbit: implications for arrhythmogenesis in humans

30 October 2018

1 reference

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Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle

30 October 2018

1 reference

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Beat-to-beat repolarization variability in ventricular myocytes and its suppression by electrical coupling.

30 October 2018

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Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes.

30 October 2018

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Cycle length-dependent action potential duration in canine cardiac Purkinje fibers.

30 October 2018

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Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide

30 October 2018

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12 December 2020

Frequency-dependent electrophysiologic effects of amiodarone in humans

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12 December 2020

Rate- and site-dependent effects of propafenone, dofetilide, and the new I(Ks)-blocking agent chromanol 293b on individual muscle layers of the intact canine heart

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12 December 2020

Combined potassium and calcium channel antagonistic activities as a basis for neutral frequency dependent increase in action potential duration: comparison between BRL-32872 and azimilide

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12 December 2020

Delayed adaptation of ventricular repolarization after sudden changes in heart rate due to conversion of atrial fibrillation. A potential risk factor for proarrhythmia?

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12 December 2020

Bepridil produces prominent bradycardia-dependent QT prolongation in patients with structural heart disease

1 reference

12 December 2020

10.1161/CIRCULATIONAHA.110.000661

Identifiers

DOI

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28 July 2017

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28 July 2017

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