Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009 (Q33654202)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722291%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009 (English)

1 reference

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13 March 2020

1 reference

1

1 reference

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13 March 2020

Chia-Ron Yang

6

1 reference

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13 March 2020

author name string

J-P Liou

2

1 reference

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13 March 2020

H-Y Lee

3

1 reference

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13 March 2020

M-J Lai

4

1 reference

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13 March 2020

Y-H Li

5

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13 March 2020

publication date

10 April 2014

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13 March 2020

published in

Cell Death and Disease

1 reference

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13 March 2020

volume

5

1 reference

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13 March 2020

page(s)

e1166

1 reference

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Edible blue-green algae reduce the production of pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes

13 March 2020

cites work

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Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

21 June 2018

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Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo

21 June 2018

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Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

21 June 2018

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Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseases.

21 June 2018

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SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease

21 June 2018

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Mechanism of action of proteasome inhibitors and deacetylase inhibitors and the biological basis of synergy in multiple myeloma

21 June 2018

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Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

21 June 2018

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Histone deacetylases as regulators of inflammation and immunity

21 June 2018

1 reference

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Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells

21 June 2018

1 reference

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Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis

21 June 2018

1 reference

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HDAC3 and HDAC7 have opposite effects on osteoclast differentiation

21 June 2018

1 reference

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Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: updated results from the British Society for Rheumatology Biologics Register with specia

21 June 2018

1 reference

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Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis

21 June 2018

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Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

21 June 2018

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The aggresome pathway as a target for therapy in hematologic malignancies

21 June 2018

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Histone deacetylase inhibitors: new hope for rheumatoid arthritis?

21 June 2018

1 reference

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HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination

21 June 2018

1 reference

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New therapies for treatment of rheumatoid arthritis

21 June 2018

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Therapeutic targets in inflammatory disease

21 June 2018

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Rheumatoid arthritis: regulation of synovial inflammation

21 June 2018

1 reference

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Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

21 June 2018

1 reference

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21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.133

1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors.

21 January 2018

1 reference

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Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

21 January 2018

1 reference

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Histone Deacetylase Inhibitor Reduces Monocyte Adhesion to Endothelium Through the Suppression of Vascular Cell Adhesion Molecule-1 Expression

21 January 2018

1 reference

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Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro

21 January 2018

1 reference

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Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL.

21 January 2018

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In vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24722291

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2014.133

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722291%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24722291%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference