Recurrent PTPRB and PLCG1 mutations in angiosarcoma (Q33657848)

28 July 2017

title

Recurrent PTPRB and PLCG1 mutations in angiosarcoma (English)

1 reference

28 July 2017

12

Elli Papaemmanuil

1 reference

28 July 2017

Sahil Seth

31

0 references

Sancha Martin

Sancha Martin

17

0 references

Peter Van Loo

Peter Van Loo

5

0 references

David C. Wedge

David C Wedge

7

0 references

Ultan McDermott

Ultan McDermott

44

0 references

Alexander J. Lazar

Alexander J Lazar

26

0 references

Adrian Harris

Adrian Harris

49

0 references

Latasha Little

27

Latasha Little

1 reference

28 July 2017

47

P Andrew Futreal

1 reference

28 July 2017

Tom D Bunney

14

0 references

Jon Teague

20

Jon W Teague

1 reference

28 July 2017

46

Michael R Stratton

1 reference

28 July 2017

4

Inigo Martincorena

1 reference

28 July 2017

6

Gunes Gundem

1 reference

28 July 2017

2

Patrick S Tarpey

1 reference

28 July 2017

8

Manasa Ramakrishna

1 reference

28 July 2017

37

Bhavisha Khatri

1 reference

28 July 2017

1

Sam Behjati

1 reference

28 July 2017

29

Alexei Protopopov

1 reference

28 July 2017

Helen Sheldon

3

1 reference

28 July 2017

Susanna L Cooke

9

1 reference

28 July 2017

Nischalan Pillay

10

1 reference

28 July 2017

Hans Kristian M Vollan

11

1 reference

28 July 2017

Hans Koss

13

1 reference

28 July 2017

Claire Hardy

15

1 reference

28 July 2017

Olivia R Joseph

16

1 reference

28 July 2017

Laura Mudie

18

1 reference

28 July 2017

Adam Butler

19

1 reference

28 July 2017

Meena Patil

21

1 reference

28 July 2017

Graham Steers

22

1 reference

28 July 2017

Yu Cao

23

1 reference

28 July 2017

Curtis Gumbs

24

1 reference

28 July 2017

Davis Ingram

25

1 reference

28 July 2017

Harshad Mahadeshwar

28

1 reference

28 July 2017

Ghadah A Al Sannaa

30

1 reference

28 July 2017

Xingzhi Song

32

1 reference

28 July 2017

Jiabin Tang

33

1 reference

28 July 2017

Jianhua Zhang

34

1 reference

28 July 2017

Vinod Ravi

35

1 reference

28 July 2017

Keila E Torres

36

1 reference

28 July 2017

Dina Halai

38

1 reference

28 July 2017

Ioannis Roxanis

39

1 reference

28 July 2017

Daniel Baumhoer

40

1 reference

28 July 2017

Roberto Tirabosco

41

1 reference

28 July 2017

M Fernanda Amary

42

1 reference

28 July 2017

Chris Boshoff

43

1 reference

28 July 2017

Matilda Katan

45

1 reference

28 July 2017

Adrienne M Flanagan

48

1 reference

28 July 2017

Peter J Campbell

50

1 reference

28 July 2017

language of work or name

English

0 references

publication date

16 March 2014

1 reference

28 July 2017

1 reference

28 July 2017

volume

46

1 reference

28 July 2017

issue

4

1 reference

28 July 2017

page(s)

376-379

1 reference

https://scigraph.springernature.com/pub.10.1038/ng.2921

28 July 2017

exact match

0 references

cites work

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Ve-ptp modulates vascular integrity by promoting adherens junction maturation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

VEGF and angiopoietin signaling in tumor angiogenesis and metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Allele-specific copy number analysis of tumors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Fast and accurate long-read alignment with Burrows-Wheeler transform

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Characterization of phospholipase C gamma enzymes with gain-of-function mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

VE-PTP controls blood vessel development by balancing Tie-2 activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

TopHat: discovering splice junctions with RNA-Seq

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Statistical analysis of pathogenicity of somatic mutations in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032873

21 June 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24633157

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.2921

1 reference

28 July 2017

1 reference

28 July 2017

1 reference