Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism (Q33658181)

28 July 2017

title

Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism (English)

1 reference

28 July 2017

Thai H Tran

1

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28 July 2017

Fransiscus E Utama

2

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28 July 2017

Justin Lin

3

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28 July 2017

Ning Yang

4

1 reference

28 July 2017

Ashley B Sjolund

5

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28 July 2017

Amy Ryder

6

1 reference

28 July 2017

Kevin J Johnson

7

1 reference

28 July 2017

Lynn M Neilson

8

1 reference

28 July 2017

Chengbao Liu

9

1 reference

28 July 2017

Kristin L Brill

10

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28 July 2017

Anne L Rosenberg

11

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28 July 2017

Agnieszka K Witkiewicz

12

1 reference

28 July 2017

Hallgeir Rui

13

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28 July 2017

language of work or name

English

0 references

publication date

2 February 2010

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28 July 2017

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28 July 2017

volume

70

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28 July 2017

issue

4

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28 July 2017

page(s)

1711-1721

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Male-specific hepatic Bcl6: growth hormone-induced block of transcription elongation in females and binding to target genes inversely coordinated with STAT5

28 July 2017

cites work

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Reciprocal effects of STAT5 and STAT3 in breast cancer

21 June 2018

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Computational and functional analysis of growth hormone (GH)-regulated genes identifies the transcriptional repressor B-cell lymphoma 6 (Bc16) as a participant in GH-regulated transcription

21 June 2018

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BCL-6 prevents mammary epithelial apoptosis and promotes cell survival

21 June 2018

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Oncogene-mediated inhibition of glycogen synthase kinase 3 beta impairs degradation of prolactin receptor

21 June 2018

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Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo

21 June 2018

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Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition

21 June 2018

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Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression

21 June 2018

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Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus

21 June 2018

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Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.

21 June 2018

1 reference

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Stat5 activation inhibits prolactin-induced AP-1 activity: distinct prolactin-initiated signals in tumorigenesis dependent on cell context.

21 June 2018

1 reference

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Stat5 in the mammary gland: controlling normal development and cancer

21 June 2018

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STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas

21 June 2018

1 reference

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Quantitative in situ analysis of beta-catenin expression in breast cancer shows decreased expression is associated with poor outcome

21 June 2018

1 reference

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Human prolactin receptors are insensitive to mouse prolactin: implications for xenotransplant modeling of human breast cancer in mice.

21 June 2018

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Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer

21 June 2018

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Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells.

21 June 2018

1 reference

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FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism.

21 June 2018

1 reference

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Signal transducer and activator of transcription-5 activation and breast cancer prognosis

21 June 2018

1 reference

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BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation

21 June 2018

1 reference

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Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice

21 June 2018

1 reference

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Bcl6 is a transcriptional repressor for the IL-18 gene

21 June 2018

1 reference

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

The role of prolactin in mammary carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Histone deacetylases (HDACs): characterization of the classical HDAC family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription

21 June 2018

1 reference

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Prolactin as a mitogen in mammary cells

21 June 2018

1 reference

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Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation

21 June 2018

1 reference

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DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites

21 June 2018

1 reference

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Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Prolactin signaling in mammary gland development.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Stat5a is mandatory for adult mammary gland development and lactogenesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Comparative genomics of susceptibility to mammary carcinogenesis among inbred rat strains: role of reduced prolactin signaling in resistance of the Copenhagen strain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Stat5 expression predicts response to endocrine therapy and improves survival in estrogen receptor-positive breast cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Local over-expression of prolactin in differentiating mouse mammary gland induces functional defects and benign lesions, but no carcinoma.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Loss of Stat5a delays mammary cancer progression in a mouse model.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822876

Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1alpha (HIF-1alpha)

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20124477

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of raf-1, MEK, and MAP kinase in prolactin responsive mammary cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20124477

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

STAT 5a expression in the breast is maintained in secretory carcinoma, in contrast to other histologic types

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20124477

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-09-2314

1 reference

28 July 2017

1 reference

28 July 2017

1 reference