Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: a key role for I(Ks). (Q33661049)

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6 February 2020

title

Dexrazoxane protects the heart from acute doxorubicin-induced QT prolongation: a key role for I(Ks) (English)

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6 February 2020

2

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6 February 2020

author name string

Joffrey Ducroq

1

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6 February 2020

S Guilbot

3

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6 February 2020

S Dilly

4

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6 February 2020

E Laemmel

5

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6 February 2020

C Pons-Himbert

6

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6 February 2020

J F Faivre

7

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6 February 2020

P Bois

8

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6 February 2020

O Stücker

9

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6 February 2020

M Le Grand

10

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6 February 2020

language of work or name

English

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publication date

24 August 2009

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British Journal of Pharmacology

6 February 2020

published in

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6 February 2020

volume

159

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6 February 2020

issue

1

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6 February 2020

page(s)

93-101

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Slow delayed rectifier potassium current (IKs) and the repolarization reserve.

6 February 2020

cites work

1 reference

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Differentiation of arrhythmia risk of the antibacterials moxifloxacin, erythromycin, and telithromycin based on analysis of monophasic action potential duration alternans and cardiac instability

21 June 2018

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Blockade of IKs by HMR 1556 increases the reverse rate-dependence of refractoriness prolongation by dofetilide in isolated rabbit ventricles

21 June 2018

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Mechanism of hERG K+ channel blockade by the fluoroquinolone antibiotic moxifloxacin

21 June 2018

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QT prolongation and proarrhythmia by moxifloxacin: concordance of preclinical models in relation to clinical outcome

21 June 2018

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Cardiovascular complications of cancer therapy: diagnosis, pathogenesis, and management

21 June 2018

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Two components of delayed rectifier K+ current in heart: molecular basis, functional diversity, and contribution to repolarization

21 June 2018

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MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

21 June 2018

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Dexrazoxane. A review of its use as a cardioprotective agent in patients receiving anthracycline-based chemotherapy

21 June 2018

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Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

21 June 2018

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K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

21 June 2018

1 reference

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Dose-response relationship of dexrazoxane for prevention of doxorubicin-induced cardiotoxicity in mice, rats, and dogs.

21 June 2018

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Doxorubicin (adriamycin) cardiomyopathy

21 June 2018

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

21 June 2018

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Acute arrhythmogenicity of doxorubicin administration

21 June 2018

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Comparison of acute effects of anthracyclines on cardiac electrophysiological parameters of isolated guinea-pig hearts

21 June 2018

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Sudden death in leukemic patients treated with doxorubicin

21 June 2018

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Effect of epirubicin-based chemotherapy and dexrazoxane supplementation on QT dispersion in non-Hodgkin lymphoma patients

21 June 2018

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The metabolites of the cardioprotective drug dexrazoxane do not protect myocytes from doxorubicin-induced cytotoxicity

21 January 2018

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Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

21 January 2018

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In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation

21 January 2018

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Effects of doxorubicinol on excitation--contraction coupling in guinea pig ventricular myocytes

21 January 2018

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Effects of doxorubicin on excitation-contraction coupling in guinea pig ventricular myocardium

21 January 2018

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Effect of a single oral dose of moxifloxacin (400 mg and 800 mg) on ventricular repolarization in healthy subjects

21 January 2018

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Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG.

21 January 2018

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QT dispersion and late potentials during doxorubicin therapy for non-Hodgkin's lymphoma

30 October 2018

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12 December 2020

Reduced repolarization reserve due to anthracycline therapy facilitates torsade de pointes induced by IKr blockers

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12 December 2020

Moxifloxacin and torsade de pointes

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12 December 2020

New chemotherapeutic agents--bleomycin and adriamycin

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12 December 2020

Evidence for two components of delayed rectifier K+ current in human ventricular myocytes

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12 December 2020

10.1111/J.1476-5381.2009.00371.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19703166%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

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6 February 2020

PubMed publication ID

19703166

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19703166%20AND%20SRC:MED&resulttype=core&format=json