ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation (Q33661520)

28 July 2017

ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation (English)

1 reference

28 July 2017

1 reference

7

Jacques Pouysségur

1 reference

28 July 2017

Janine N Post

3

0 references

Diane S. Lidke

1

object named as

Diane S Lidke

1 reference

28 July 2017

Fang Huang

2

1 reference

28 July 2017

Bernd Rieger

4

1 reference

28 July 2017

Julie Wilsbacher

5

1 reference

28 July 2017

James L Thomas

6

1 reference

28 July 2017

Thomas M Jovin

8

1 reference

28 July 2017

Philippe Lenormand

9

1 reference

28 July 2017

language of work or name

English

0 references

publication date

17 November 2009

1 reference

Journal of Biological Chemistry

28 July 2017

1 reference

28 July 2017

285

1 reference

28 July 2017

5

1 reference

28 July 2017

3092-3102

1 reference

Measurement of submicron laser beam radii

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Essential role of ERK dimers in the activation of cytoplasmic but not nuclear substrates by ERK-scaffold complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Dynamic regulation of ERK2 nuclear translocation and mobility in living cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Akt down-regulates ERK1/2 nuclear localization and angiotensin II-induced cell proliferation through PEA-15.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Targeting the ERK signaling pathway in cancer therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Active ERK1 is dimerized in vivo: bisphosphodimers generate peak kinase activity and monophosphodimers maintain basal ERK1 activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Regulated fast nucleocytoplasmic shuttling observed by reversible protein highlighting

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Live Cell Imaging of ERK and MEK: simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Vanishin is a novel ubiquitinylated death-effector domain protein that blocks ERK activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Sef is a spatial regulator for Ras/MAP kinase signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Imaging molecular interactions in cells by dynamic and static fluorescence anisotropy (rFLIM and emFRET).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

ERK2 enters the nucleus by a carrier-independent mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

The photoreceptor sensory rhodopsin I as a two-photon-driven proton pump

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Homo-FRET microscopy in living cells to measure monomer-dimer transition of GFP-tagged proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Accessing molecular dynamics in cells by fluorescence correlation spectroscopy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

A conserved docking motif in MAP kinases common to substrates, activators and regulators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Fluorescence correlation spectroscopy. II. An experimental realization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Evidence for existence of a nuclear pore complex-mediated, cytosol-independent pathway of nuclear translocation of ERK MAP kinase in permeabilized cells.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

The nuclear localization of ERK2 occurs by mechanisms both independent of and dependent on energy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

Characterization of mitogen-activated protein kinase (MAPK) dimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

Examining the mechanism of Erk nuclear translocation using green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

The role of photon statistics in fluorescence anisotropy imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

Fluorescence correlation spectroscopy. I. Conceptual basis and theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

Identification and characterization of a general nuclear translocation signal in signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823437

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

30 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064972

Mutations in ERK2 Binding Sites Affect Nuclear Entry

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19920141

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluorescence correlation spectroscopy as a tool to investigate chemical reactions in solutions and on cell surfaces

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19920141

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nuclear shuttling of mitogen-activated protein (MAP) kinase (extracellular signal-regulated kinase (ERK) 2) was dynamically controlled by MAP/ERK kinase after antigen stimulation in RBL-2H3 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19920141

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.064972

1 reference

28 July 2017

1 reference

28 July 2017

1 reference