Binding of alpha-synuclein with Fe(III) and with Fe(II) and biological implications of the resultant complexes. (Q33665421)

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15 January 2020

title

Binding of alpha-synuclein with Fe(III) and with Fe(II) and biological implications of the resultant complexes (English)

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15 January 2020

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3

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15 January 2020

You-Nian Liu

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15 January 2020

author name string

Yong Peng

1

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15 January 2020

Chengshan Wang

2

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15 January 2020

Feimeng Zhou

5

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publication date

18 November 2009

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Journal of Inorganic Biochemistry

15 January 2020

published in

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15 January 2020

volume

104

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15 January 2020

issue

4

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15 January 2020

page(s)

365-370

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Ternary complexes of iron, amyloid-beta, and nitrilotriacetic acid: binding affinities, redox properties, and relevance to iron-induced oxidative stress in Alzheimer's disease

15 January 2020

cites work

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Copper(II) binding to alpha-synuclein, the Parkinson's protein

14 July 2018

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Role of different regions of alpha-synuclein in the assembly of fibrils.

14 July 2018

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Redox reactions of copper complexes formed with different beta-amyloid peptides and their neuropathological [correction of neuropathalogical] relevance

14 July 2018

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Copper and iron disorders of the brain

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The aggregation and fibrillation of alpha-synuclein

14 July 2018

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The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy

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Nosology of Parkinson's disease: looking for the way out of a quagmire

14 July 2018

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Molecular pathophysiology of Parkinson's disease

14 July 2018

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Calcium(II) selectively induces alpha-synuclein annular oligomers via interaction with the C-terminal domain

14 July 2018

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Oxidative stress in Parkinson's disease

14 July 2018

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The influence of the synergistic anion on iron chelation by ferric binding protein, a bacterial transferrin

14 July 2018

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The labile iron pool: characterization, measurement, and participation in cellular processes(1).

14 July 2018

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Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein

14 July 2018

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Location and properties of metal-binding sites on the human prion protein.

14 July 2018

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(E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease

14 July 2018

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

14 July 2018

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A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease.

14 July 2018

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Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.

14 July 2018

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Alpha-synuclein in Lewy bodies

14 July 2018

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Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

14 July 2018

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Reactive oxygen species and the central nervous system

14 July 2018

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Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers

14 July 2018

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Metal ions differentially influence the aggregation and deposition of Alzheimer's beta-amyloid on a solid template

30 October 2018

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Alpha-synuclein adopts an alpha-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation.

30 October 2018

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Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

30 October 2018

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Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding

30 October 2018

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Lipid interaction of alpha-synuclein during the metal-catalyzed oxidation in the presence of Cu2+ and H2O2.

30 October 2018

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Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes

30 October 2018

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Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure

30 October 2018

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The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

30 October 2018

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12 December 2020

Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments

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12 December 2020

Interaction of α-Synuclein with Divalent Metal Ions Reveals Key Differences: A Link between Structure, Binding Specificity and Fibrillation Enhancement

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12 December 2020

Critical oxygen tension in rat brain: a combined (31)P-NMR and EPR oximetry study

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12 December 2020

Sequestration of iron by Lewy bodies in Parkinson's disease

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12 December 2020

Estimation of the ferrous-transferrin binding constants based on thermodynamic studies of nickel(II)-transferrin

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12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

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12 December 2020

10.1016/J.JINORGBIO.2009.11.005

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20005574%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20005574%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

20005574

1 reference