PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity (Q33665491)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19857534%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity (English)

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11 February 2020

5

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author name string

Jun-Beom Park

1

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11 February 2020

Young Min Kwon

2

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11 February 2020

Tien-Yi Lee

3

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11 February 2020

Remy Brim

4

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11 February 2020

Roger K Sunahara

6

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11 February 2020

James H Woods

7

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11 February 2020

Victor C Yang

8

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11 February 2020

language of work or name

English

0 references

publication date

24 October 2009

1 reference

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Journal of Controlled Release

11 February 2020

published in

1 reference

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volume

142

1 reference

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issue

2

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page(s)

174-179

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describes a project that uses

11 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2824037/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Pegaptanib sodium for macular edema secondary to central retinal vein occlusion

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Enzymatic activity and thermal stability of PEG-alpha-chymotrypsin conjugates

21 June 2018

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Effects of cocaine esterase following its repeated administration with cocaine in mice

21 June 2018

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Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity

21 June 2018

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Stabilization of alpha-chymotrypsin upon PEGylation correlates with reduced structural dynamics

21 June 2018

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Antitumoral activity of PEG-gemcitabine prodrugs targeted by folic acid

21 June 2018

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Improved intrapulmonary delivery of site-specific PEGylated salmon calcitonin: optimization by PEG size selection

21 June 2018

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Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL11) by chemical modification with polyethylene glycol

21 June 2018

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A long-acting, mono-PEGylated human growth hormone analog is a potent stimulator of weight gain and bone growth in hypophysectomized rats

21 June 2018

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PEG conjugated VEGF siRNA for anti-angiogenic gene therapy

21 June 2018

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PEGylation, successful approach to drug delivery

21 June 2018

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Toward cocaine esterase therapeutics

21 June 2018

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Site-directed PEGylation of trichosanthin retained its anti-HIV activity with reduced potency in vitro

21 June 2018

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The Rhodococcus sp. Cocaine Esterase: A Bacterial Candidate for Novel Pharmacokinetic‐based Therapies for Cocaine Abuse

21 June 2018

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Pegaspargase: a review of clinical studies

21 June 2018

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Pharmacokinetic and biodistribution properties of poly(ethylene glycol)–protein conjugates

21 June 2018

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Biochemical characterization and structural analysis of a highly proficient cocaine esterase

21 June 2018

1 reference

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Crystal structure of a bacterial cocaine esterase

21 June 2018

1 reference

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Preparation and characterization of PEGylated adducts of recombinant human tumor necrosis factor-alpha from Escherichia coli

21 June 2018

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21 June 2018

PEG drugs: an overview

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Improvements in protein PEGylation: pegylated interferons for treatment of hepatitis C.

21 June 2018

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Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C.

21 June 2018

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Peptide and protein PEGylation: a review of problems and solutions

21 June 2018

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Cocaine esterase: interactions with cocaine and immune responses in mice

21 June 2018

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Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase

30 October 2018

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PEGylated interferon-alpha2b: a branched 40K polyethylene glycol derivative

30 October 2018

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Preclinical and phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration

30 October 2018

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Anticancer drug delivery systems: multi-loaded N4-acyl poly(ethylene glycol) prodrugs of ara-C. II. Efficacy in ascites and solid tumors

30 October 2018

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Reducing the immunogenicity and improving the in vivo activity of trichosanthin by site-directed pegylation.

30 October 2018

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Long-acting growth hormones produced by conjugation with polyethylene glycol.

30 October 2018

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N-terminal site-specific mono-PEGylation of epidermal growth factor

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19857534

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JCONREL.2009.10.015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19857534%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

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11 February 2020

PubMed publication ID

19857534

1 reference