Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction. (Q33668240)

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19 January 2020

title

Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction (English)

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19 January 2020

2

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19 January 2020

author name string

Zhong-Ze Fang

1

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19 January 2020

Guang-Bo Ge

3

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19 January 2020

Hong Huo

4

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19 January 2020

Si-Cheng Liang

5

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19 January 2020

Ling Yang

6

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19 January 2020

language of work or name

English

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publication date

1 February 2010

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British Journal of Clinical Pharmacology

19 January 2020

published in

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19 January 2020

volume

69

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19 January 2020

issue

2

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19 January 2020

page(s)

193-199

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p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells

19 January 2020

cites work

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Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth

21 June 2018

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Protein measurement with the Folin phenol reagent

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

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21 June 2018

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Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation

21 June 2018

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Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells

21 June 2018

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Human P450 metabolism of warfarin

21 June 2018

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Studies on the fate of 3H-noscapine in mice and rats

21 June 2018

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Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel

21 June 2018

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UDP-glucuronosyltransferase 1A6 is the major isozyme responsible for protocatechuic aldehyde glucuronidation in human liver microsomes.

30 October 2018

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Warfarin-noscapine interaction: a series of four case reports

30 October 2018

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Noscapine may increase the effect of warfarin

30 October 2018

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Potential interaction between telithromycin and warfarin

30 October 2018

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The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties.

30 October 2018

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Mechanism-based inactivation of human cytochrome p450 enzymes and the prediction of drug-drug interactions

30 October 2018

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12 December 2020

Comparison of the antitussive effects of codeine phosphate 20 mg, dextromethorphan 30 mg and noscapine 30 mg using citric acid-induced cough in normal subjects

1 reference

12 December 2020

Pharmacokinetics of oral noscapine

1 reference

12 December 2020

Pharmacokinetic interaction between warfarin and a uricosuric agent, bucolome: application of In vitro approaches to predicting In vivo reduction of (S)-warfarin clearance

1 reference

12 December 2020

Rofecoxib Is a Potent, Metabolism-Dependent Inhibitor of CYP1A2: Implications for in Vitro Prediction of Drug Interactions

1 reference

12 December 2020

Preclinical pharmacokinetics and bioavailability of noscapine, a tubulin-binding anticancer agent

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12 December 2020

10.1111/J.1365-2125.2009.03572.X

Identifiers

DOI

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19 January 2020

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19 January 2020

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