Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. (Q33671906)

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English	Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.	scientific article

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8 January 2020

Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients (English)

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8 January 2020

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Matlock Jeffries

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8 January 2020

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A H Sawalha

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8 January 2020

R Webb

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8 January 2020

Q Lu

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8 January 2020

G Gorelik

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8 January 2020

D Ray

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8 January 2020

J Osban

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8 January 2020

N Knowlton

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8 January 2020

K Johnson

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8 January 2020

B Richardson

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8 January 2020

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1 June 2008

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8 January 2020

Genes and Immunity

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8 January 2020

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8 January 2020

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8 January 2020

368-378

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8 January 2020

https://scigraph.springernature.com/pub.10.1038/gene.2008.29

0 references

High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

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21 June 2018

Current status of lupus genetics

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21 June 2018

Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells

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21 June 2018

Environment and systemic lupus erythematosus: an overview

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Procainamide is a specific inhibitor of DNA methyltransferase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Interferon-alpha in systemic lupus erythematosus

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21 June 2018

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

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21 June 2018

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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21 June 2018

Role of DNA methylation in the regulation of cell function

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21 June 2018

An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Inducible expression of a mutant form of MEK1 in Swiss 3T3 cells

2 references

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21 June 2018

https://api.crossref.org/works/10.1038%2FGENE.2008.29

7 January 2021

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Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Regulation of DNA methylation by the Ras signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Prognostic value of anti-dsDNA in SLE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Hydralazine, antinuclear antibodies, and the lupus syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Procainamide inhibits DNA methyltransferase in a human T cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Amplified RNA synthesized from limited quantities of heterogeneous cDNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Use of restriction enzymes to study eukaryotic DNA methylation: II. The symmetry of methylated sites supports semi-conservative copying of the methylation pattern.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

21 June 2018

Effect of DNA methylation and chromatin structure on ITGAL expression

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Demethylation of CD40LG on the inactive X in T cells from women with lupus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Hydralazine may induce autoimmunity by inhibiting extracellular signal-regulated kinase pathway signaling

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2008.29

21 January 2018

Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients

1 reference

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21 January 2018

A random variance model for detection of differential gene expression in small microarray experiments

1 reference

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21 January 2018

Minocycline induced lupus: case series in the West of Scotland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825163

30 October 2018

Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocyte function—associated antigen 1 overexpression and t cell autoreactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of drug-induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the ras-MAPK signaling pathway in the DNA methyltransferase response to DNA hypomethylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of an inhibitor of DNA methylation on T cells. II. 5-Azacytidine induces self-reactivity in antigen-specific T4+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic view of systemic autoimmunity in MRLlpr mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective DNA methylation and CD70 overexpression in CD4+ T cells in MRL/lpr lupus-prone mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523434

12 December 2020

based on heuristic

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Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes

1 reference

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12 December 2020

based on heuristic

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Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients

1 reference

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12 December 2020

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Interferon-gamma is required for lupus nephritis in mice treated with the hydrocarbon oil pristane

1 reference

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12 December 2020

based on heuristic

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10.1038/GENE.2008.29

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8 January 2020

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8 January 2020

PubMed publication ID

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8 January 2020

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