Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth (Q33674790)

28 July 2017

title

Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth (English)

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28 July 2017

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15

Anita B Hjelmeland

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13

Roger E McLendon

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2

Justin D Lathia

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16

Jeremy N Rich

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28 July 2017

Hui Wang

1

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28 July 2017

Qiulian Wu

3

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28 July 2017

Jialiang Wang

4

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28 July 2017

Zhizhong Li

5

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28 July 2017

John M Heddleston

6

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28 July 2017

Christine E Eyler

7

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28 July 2017

Jennifer Elderbroom

8

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Joseph Gallagher

9

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Jesse Schuschu

10

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Jennifer MacSwords

11

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28 July 2017

Yiting Cao

12

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Xiao-Fan Wang

14

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28 July 2017

publication date

1 October 2009

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volume

27

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28 July 2017

issue

10

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28 July 2017

page(s)

2393-2404

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

28 July 2017

cites work

1 reference

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Targeting cancer stem cells through L1CAM suppresses glioma growth

14 July 2018

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JSI-124 inhibits glioblastoma multiforme cell proliferation through G(2)/M cell cycle arrest and apoptosis augment

14 July 2018

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Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells

14 July 2018

1 reference

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IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

14 July 2018

1 reference

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Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

14 July 2018

1 reference

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Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

14 July 2018

1 reference

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Interleukin-6 gene amplification and shortened survival in glioblastoma patients.

14 July 2018

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Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

14 July 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

14 July 2018

1 reference

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Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

14 July 2018

1 reference

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The role of IL-6 and STAT3 in inflammation and cancer

14 July 2018

1 reference

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Interleukin-6: from basic science to medicine--40 years in immunology

14 July 2018

1 reference

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Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1.

14 July 2018

1 reference

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Identification of human brain tumour initiating cells

14 July 2018

1 reference

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Cancerous stem cells can arise from pediatric brain tumors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence.

14 July 2018

1 reference

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Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Fas engagement increases expression of interleukin-6 in human glioma cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Hypoxia--a key regulatory factor in tumour growth

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Interleukin-6 (IL-6) does not change the expression of Bcl-2 protein in the prevention of cisplatin-induced apoptosis in ovarian cancer cell lines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Interleukin-6 enhances motility of breast carcinoma cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Stem cell marker CD133 affects clinical outcome in glioma patients.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Bevacizumab plus irinotecan in recurrent glioblastoma multiforme

30 October 2018

1 reference

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Chemotherapy resistance of glioblastoma stem cells

30 October 2018

1 reference

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Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

IL-6 is required for glioma development in a mouse model

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825688

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19658188

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/STEM.188

1 reference

28 July 2017

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28 July 2017

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