Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy (Q33675261)

28 July 2017

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy (English)

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28 July 2017

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6

Herschel A Rabitz

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28 July 2017

1

Joshua Munger

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28 July 2017

Bryson D Bennett

2

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28 July 2017

Anuraag Parikh

3

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28 July 2017

Xiao-Jiang Feng

4

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28 July 2017

Jessica McArdle

5

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28 July 2017

Thomas Shenk

7

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28 July 2017

Joshua D Rabinowitz

8

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28 July 2017

28 September 2008

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28 July 2017

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28 July 2017

26

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28 July 2017

1179-1186

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28 July 2017

10

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https://scigraph.springernature.com/pub.10.1038/nbt.1500

28 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

21 June 2018

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UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells

21 June 2018

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Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

21 June 2018

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ATP citrate lyase is an important component of cell growth and transformation

21 June 2018

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Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

21 June 2018

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Epidemiology, pathogenesis and prevention of congenital cytomegalovirus infection

21 June 2018

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Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome

21 June 2018

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Pathogenesis of human cytomegalovirus infection and cellular targets

21 June 2018

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Optimal identification of biochemical reaction networks

21 June 2018

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Metabolic biomarker and kinase drug target discovery in cancer using stable isotope-based dynamic metabolic profiling (SIDMAP).

21 June 2018

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On the Origin of Cancer Cells

21 June 2018

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Human cytomegalovirus UL99-encoded pp28 is required for the cytoplasmic envelopment of tegument-associated capsids.

21 June 2018

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Metabonomics: a platform for studying drug toxicity and gene function

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Metabolomics – the link between genotypes and phenotypes

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

21 June 2018

12 December 2020

Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

DNA microarrays of the complex human cytomegalovirus genome: profiling kinetic class with drug sensitivity of viral gene expression

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Biosynthetically directed fractional 13C-labeling of proteinogenic amino acids. An efficient analytical tool to investigate intermediary metabolism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Mathematical analysis of isotope labeling in the citric acid cycle with applications to 13C NMR studies in perfused rat hearts.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Viruses budding from either the apical or the basolateral plasma membrane domain of MDCK cells have unique phospholipid compositions

21 June 2018

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The transfer of myristic and other fatty acids on lipid and viral protein acceptors in cultured cells infected with Semliki Forest and influenza virus

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Growth characteristics of cytomegalovirus in human fibroblasts with demonstration of protein synthesis early in viral replication

21 June 2018

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Regulation and Physiological Functions of Malic Enzymes

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Human cytomegalovirus stimulates host cell RNA synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Metabolomics identifies perturbations in human disorders of propionate metabolism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Simultaneous determination of multiple intracellular metabolites in glycolysis, pentose phosphate pathway and tricarboxylic acid cycle by liquid chromatography-mass spectrometry.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Kinetic flux profiling of nitrogen assimilation in Escherichia coli.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Metabolomic identification of novel biomarkers of myocardial ischemia.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of (13)C-labeled primary metabolites

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Global metabolic response of Escherichia coli to gnd or zwf gene-knockout, based on 13C-labeling experiments and the measurement of enzyme activities

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Does Cytomegalovirus Play a Role in Atherosclerosis?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Dosing of intravenous ganciclovir for the prophylaxis and treatment of cytomegalovirus infection in solid organ transplant recipients.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Cerulenin inhibits production of mature virion particles in chick embryo fibroblasts infected by influenza A viruses

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Toxicity and teratogenicity studies with the hypolipidemic drug RMI 14,514 in rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2825756

Inhibition of fatty acid synthesis by RMI 14,514 (5-tetradecyloxy-2-furoic acid)

30 October 2018

1 reference

12 December 2020

Human cytomegalovirus-induced reduction of extracellular matrix proteins in vascular smooth muscle cell cultures: a pathomechanism in vasculopathies?

1 reference

12 December 2020

Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines

1 reference

12 December 2020

Calculation of absolute metabolic flux and the elucidation of the pathways of glutamate labeling in perfused rat heart by 13C NMR spectroscopy and nonlinear least squares analysis

1 reference

12 December 2020

Widespread presence of histologically occult cytomegalovirus

1 reference

12 December 2020

Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells

1 reference

12 December 2020

Early Enhanced Glucose Uptake in Human Cytomegalovirus-infected Cells

1 reference

12 December 2020

Glutamine transport by the blood-brain barrier: a possible mechanism for nitrogen removal.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.1500

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NBT.1500

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference