The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis (Q33677805)

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13 February 2020

title

The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis (English)

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13 February 2020

3

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13 February 2020

author name string

Georg Martiny-Baron

1

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13 February 2020

Philipp Holzer

2

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13 February 2020

Christian Schnell

4

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13 February 2020

Joseph Brueggen

5

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13 February 2020

Mireille Ferretti

6

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13 February 2020

Niko Schmiedeberg

7

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13 February 2020

Jeanette M Wood

8

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13 February 2020

Pascal Furet

9

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13 February 2020

Patricia Imbach

10

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13 February 2020

publication date

29 August 2010

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13 February 2020

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13 February 2020

volume

13

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13 February 2020

issue

3

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13 February 2020

page(s)

259-267

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Creative Commons Attribution-NonCommercial 2.0 Generic

13 February 2020

copyright license

start time

29 August 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Comparison of EphA receptor tyrosine kinases and ephrinA ligand expression to EphB-ephrinB in vascularized corneas.

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The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

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The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth

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Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization

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Investigation of the expression of the EphB4 receptor tyrosine kinase in prostate carcinoma.

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Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

21 June 2018

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EphB receptor activity suppresses colorectal cancer progression

21 June 2018

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EphB4 expression and biological significance in prostate cancer

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Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization

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EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity

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In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor

30 October 2018

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Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity

30 October 2018

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30 October 2018

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EphB4 receptor tyrosine kinase transgenic mice develop glomerulopathies reminiscent of aglomerular vascular shunts

30 October 2018

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Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma

30 October 2018

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Cardiovascular ephrinB2 function is essential for embryonic angiogenesis.

30 October 2018

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EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin 1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20803239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New potential ligand-receptor signaling loops in ovarian cancer identified in multiple gene expression studies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20803239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S10456-010-9183-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20803239%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20803239%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

20803239

1 reference