Leptin and its potential role in human obesity (Q33680494)

28 July 2017

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title

Leptin and its potential role in human obesity (English)

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28 July 2017

Lönnqvist F

1

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28 July 2017

Nordfors L

series ordinal

2

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28 July 2017

Schalling M

series ordinal

3

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28 July 2017

language of work or name

English

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publication date

1 June 1999

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Journal of Internal Medicine

28 July 2017

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28 July 2017

245

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28 July 2017

6

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28 July 2017

643-652

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A twin study of human obesity.

28 July 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

The role of depot fat in the hypothalamic control of food intake in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Obese, a new mutation in the house mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Molecular mapping of the mouse ob mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Leptin secretion from adipose tissue in women. Relationship to plasma levels and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

The role of neuropeptide Y in the antiobesity action of the obese gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Modulation of insulin activities by leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Role of leptin in the neuroendocrine response to fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Human blood-brain barrier leptin receptor. Binding and endocytosis in isolated human brain microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Leptin activation in hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Leptin receptor missense mutation in the fatty Zucker rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

A receptor subtype involved in neuropeptide-Y-induced food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Increased obese mRNA expression in omental fat cells from massively obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Human leptin levels are pulsatile and inversely related to pituitary-adrenal function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Nocturnal rise of leptin in lean, obese, and non-insulin-dependent diabetes mellitus subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Responses of leptin to short-term fasting and refeeding in humans: a link with ketogenesis but not ketones themselves

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Low leptin levels predict amenorrhea in underweight and eating disordered females

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Absence of mutations in the human OB gene in obese/diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Amino acid variants in the human leptin receptor: lack of association to juvenile onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Indication for linkage of the human OB gene region with extreme obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Extreme obesity may be linked to markers flanking the human OB gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Leptin concentrations in diabetic and nondiabetic Mexican-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Serum leptin concentrations correlate to plasma insulin concentrations independent of body fat content in chronic renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Acute and chronic effects of insulin on leptin production in humans: Studies in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Glucocorticoids as counterregulatory hormones of leptin: toward an understanding of leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Crystal structure of the obese protein leptin-E100

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Activation of beta(3) adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Pharmacologic manipulation of ob expression in a dietary model of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2796.1999.00493.X

10.1046/J.1365-2796.1999.00493.X

21 January 2018

Identifiers

DOI

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28 July 2017

1 reference