HIV-1 pathogenesis and therapeutic intervention in the SCID-hu Thy/Liv mouse: a model for primary HIV-1 infection in the human thymus (Q33682963)

28 July 2017

HIV-1 pathogenesis and therapeutic intervention in the SCID-hu Thy/Liv mouse: a model for primary HIV-1 infection in the human thymus (English)

1 reference

28 July 2017

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Su L

1

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28 July 2017

1 September 1997

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Reviews in Medical Virology

28 July 2017

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28 July 2017

7

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28 July 2017

3

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28 July 2017

157-166

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RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Hematopoietic stem cell-based gene therapy for acquired immunodeficiency syndrome: efficient transduction and expression of RevM10 in myeloid cells in vivo and in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Identification of HIV-1 determinants for replication in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

High-efficiency transduction of human lymphoid progenitor cells and expression in differentiated T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Host factors and the pathogenesis of HIV-induced disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

HIV-1-associated pathology in hemato-lymphoid organs and the experimental evaluation in the SCID-hu mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

The SCID-hu mouse as a model for HIV-1 infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Differentiation of CD3-4-8- human fetal thymocytes in vivo: characterization of a CD3-4+8- intermediate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Disseminated human immunodeficiency virus 1 (HIV-1) infection in SCID-hu mice after peripheral inoculation with HIV-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Multifactorial nature of human immunodeficiency virus disease: implications for therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Primary stage of feline immunodeficiency virus infection: viral dissemination and cellular targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Rapid loss of CD4+ T cells in human-PBL-SCID mice by noncytopathic HIV isolates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

In vivo pathogenic properties of two clonal human immunodeficiency virus type 1 isolates.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Dose-dependent systemic human immunodeficiency virus infection of SCID-hu mice after intraperitoneal virus injection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Umbilical cord blood cell transduction by retroviral vectors: preclinical studies to optimize gene transfer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Molecular cloning and characterization of the HTLV-III virus associated with AIDS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Pathologic appraisal of the thymus gland in acquired immunodeficiency syndrome in children. A study of four cases and a review of the literature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Risk of human immunodeficiency virus (HIV-1) infection among laboratory workers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Biologic features of HIV-1 that correlate with virulence in the host

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

The thymus in acquired immune deficiency syndrome. Comparison with other types of immunodeficiency diseases, and presence of components of human immunodeficiency virus type 1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Long-term human hematopoiesis in the SCID-hu mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Preclinical evaluation of antiviral compounds in the SCID-hu mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Postexposure prophylaxis with zidovudine suppresses human immunodeficiency virus type 1 infection in SCID-hu mice in a time-dependent manner

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Thymus in simian immunodeficiency virus-infected rhesus monkeys.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

The SCID-hu mouse: a small animal model for HIV infection and pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

HIV infection of the adult thymus: an even more conventional theory explaining CD4 cell decrease and CD8 cell increase in AIDS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Infection of human thymic lymphocytes by HIV-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

The cytopathic effect of HIV is associated with apoptosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Thymic selection of the human T cell receptor V beta repertoire in SCID-hu mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Inhibition of human immunodeficiency virus type 1 replication in human T cells by retroviral-mediated gene transfer of a dominant-negative Rev trans-activator

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Isolation of a candidate human hematopoietic stem-cell population

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Human hematopoietic cells and thymic epithelial cells induce tolerance via different mechanisms in the SCID-hu mouse thymus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Precursors of CD3+CD4+CD8+ cells in the human thymus are defined by expression of CD34. Delineation of early events in human thymic development

21 June 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

HIV induces thymus depletion in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

21 January 2018

How does HIV cause AIDS?

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

An immunoendocrinological hypothesis of HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Early Progression of Disease in HIV-Infected Infants with Thymus Dysfunction

30 October 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

Divergent effects of chronic HIV-1 infection on human thymocyte maturation in SCID-hu mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4435957

Frequent and early in utero HIV-1 infection

30 October 2018

1 reference

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Selective thymocyte depletion in neonatal HIV-1 thymic infection

21 January 2018

1 reference

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Precocious thymic involution manifest by epithelial injury in the acquired immune deficiency syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

Infection of the SCID-hu mouse by HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291099-1654%28199709%297%3A3%3C157%3A%3AAID-RMV197%3E3.0.CO%3B2-R

Suppression of HIV infection in AZT-treated SCID-hu mice

21 January 2018

1 reference

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Indirect mechanisms of HIV pathogenesis: how does HIV kill T cells?

21 January 2018

1 reference

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A molecular genetic intervention for AIDS--effects of a transdominant negative form of Rev

21 January 2018

1 reference

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Human T-cell development in SCID-hu mice: staphylococcal enterotoxins induce specific clonal deletions, proliferation, and anergy

21 January 2018

1 reference

12 December 2020

Gene transfer into hematopoietic stem cells

1 reference

12 December 2020

Human allogeneic stem cell maintenance and differentiation in a long-term multilineage SCID-hu graft

1 reference

12 December 2020

Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent

1 reference

12 December 2020

10.1002/(SICI)1099-1654(199709)7:3<157::AID-RMV197>3.0.CO;2-R

Identifiers

DOI

1 reference

release_57q6c3q2fvf4jeamile2anqoku

28 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/57q6c3q2fvf4jeamile2anqoku

24 November 2022

mapped directly with Wikidata item

PMCID

4435957

1 reference

28 July 2017

1 reference

PubMed ID

10398480