CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies (Q33687979)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19554032%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies (English)

1 reference

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1 February 2020

1 reference

4

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1 February 2020

author name string

S S Seregin

1

1 reference

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1 February 2020

Y A Aldhamen

2

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1 February 2020

D M Appledorn

3

1 reference

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1 February 2020

A J McBride

5

1 reference

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1 February 2020

M Bujold

6

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1 February 2020

S S Godbehere

7

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1 February 2020

A Amalfitano

8

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1 February 2020

publication date

25 June 2009

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1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19554032%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

16

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1 February 2020

issue

10

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1 February 2020

page(s)

1245-1259

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19554032%20AND%20SRC:MED&resulttype=core&format=json

Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo.

1 February 2020

cites work

1 reference

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Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.

21 June 2018

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Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complement

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Complement is an essential component of the immune response to adeno-associated virus vectors

21 June 2018

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21 June 2018

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21 June 2018

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Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages.

21 June 2018

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T-cell regulation: with complements from innate immunity

21 June 2018

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Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

21 June 2018

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Adenoviral infection induces a multi-faceted innate cellular immune response that is mediated by the toll-like receptor pathway in A549 cells

21 June 2018

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Complement receptor 2, natural antibodies and innate immunity: Inter-relationships in B cell selection and activation

21 June 2018

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Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system.

21 June 2018

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Neutrophils interact with adenovirus vectors via Fc receptors and complement receptor 1.

21 June 2018

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Complement and Toll-like receptors: key regulators of adaptive immune responses

21 June 2018

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Complement: central to innate immunity and bridging to adaptive responses.

21 June 2018

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Chemokines: role in inflammation and immune surveillance

21 June 2018

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Complement: a unique innate immune sensor for danger signals

21 June 2018

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The complement system in B cell regulation

21 June 2018

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Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors

21 June 2018

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Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

21 June 2018

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21 June 2018

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21 June 2018

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CD19-CD21 complex regulates an intrinsic Src family kinase amplification loop that links innate immunity with B-lymphocyte intracellular calcium responses

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Immunomodulatory functions of murine CR1/2.

21 June 2018

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Role of complement receptors CD21/CD35 in B lymphocyte activation and survival

21 June 2018

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Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted

21 June 2018

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21 June 2018

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The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

21 June 2018

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Type I IFN signaling on both B and CD4 T cells is required for protective antibody response to adenovirus

21 June 2018

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Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent

21 January 2018

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Type I interferon inhibits antibody responses induced by a chimpanzee adenovirus vector.

30 October 2018

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DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity.

30 October 2018

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Rapid Kupffer cell death after intravenous injection of adenovirus vectors

30 October 2018

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Bioluminescence imaging reveals a significant role for complement in liver transduction following intravenous delivery of adenovirus

30 October 2018

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The role of selectins and integrins in adenovirus vector-induced neutrophil recruitment to the liver

30 October 2018

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Persistence of an [E1-, polymerase-] adenovirus vector despite transduction of a neoantigen into immune-competent mice

30 October 2018

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CD21 augments antigen presentation in immune individuals

30 October 2018

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A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: a potential mechanism for mast cell activation

30 October 2018

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12 December 2020

Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses

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12 December 2020

Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19

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12 December 2020

Soluble E-selectin, ICAM-1 and VCAM-1 levels in systemic and coronary circulation in patients with variant angina

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12 December 2020

Complement receptor 1 and 2 deficiency increases coxsackievirus B3-induced myocarditis, dilated cardiomyopathy, and heart failure by increasing macrophages, IL-1beta, and immune complex deposition in the heart

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12 December 2020

Identifiers

DOI

10.1038/GT.2009.77

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19554032%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19554032%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

19554032

1 reference