The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C. (Q33688099)

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English	The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C.	scientific article

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13 February 2020

The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C (English)

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Mayte Suárez-Fariñas

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Mayte Suárez-Fariñas

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James G. Krueger

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James G Krueger

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Dariush Moussai

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Hiroshi Mitsui

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Julia S Pettersen

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Katherine C Pierson

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Kejal R Shah

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Irma R Cardinale

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Mark J Bluth

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9 September 2010

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Journal of Investigative Dermatology

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131

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229-236

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1

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13 February 2020

https://scigraph.springernature.com/pub.10.1038/jid.2010.266

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Prognostic significance of vascular endothelial growth factor-C expression and lymphatic vessel density in supraglottic squamous cell carcinoma.

1 reference

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LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan

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Myeloid dendritic cells from human cutaneous squamous cell carcinoma are poor stimulators of T-cell proliferation

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High LYVE-1-positive lymphatic vessel numbers are associated with poor outcome in breast cancer

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The role of VEGF-C staining in predicting regional metastasis in melanoma.

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Vascular endothelial growth factor C induces angiogenesis in vivo.

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Blocking neuropilin-2 function inhibits tumor cell metastasis

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Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions

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VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

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7 January 2021

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Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration

1 reference

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A previously unknown dermal blood vessel phenotype in skin inflammation.

1 reference

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Genomic Analysis Defines a Cancer-Specific Gene Expression Signature for Human Squamous Cell Carcinoma and Distinguishes Malignant Hyperproliferation from Benign Hyperplasia

1 reference

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Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells

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VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites

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7 January 2021

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A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

1 reference

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Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution.

1 reference

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The chemokine system -- a major regulator of angiogenesis in health and disease

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Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis

1 reference

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GSEA-P: a desktop application for Gene Set Enrichment Analysis.

1 reference

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7 January 2021

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VEGF-C and VEGF-D expression is correlated with lymphatic vessel density and lymph node metastasis in oral squamous cell carcinoma: Implications for use as a prognostic marker.

1 reference

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High-risk cutaneous squamous cell carcinoma of the head and neck: results from 266 treated patients with metastatic lymph node disease

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Role of macrophages in inflammatory lymphangiogenesis: Enhanced production of vascular endothelial growth factor C and D through NF-kappaB activation

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Prox1 function is required for the development of the murine lymphatic system

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Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.266

7 January 2021

based on heuristic

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10.1038/JID.2010.266

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13 February 2020

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13 February 2020

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