Should prolactin be reconsidered as a therapeutic target in human breast cancer? (Q33690324)

28 July 2017

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title

Should prolactin be reconsidered as a therapeutic target in human breast cancer? (English)

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28 July 2017

Goffin V

1

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28 July 2017

Touraine P

2

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28 July 2017

Pichard C

3

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28 July 2017

Bernichtein S

4

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28 July 2017

Kelly PA

5

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28 July 2017

1 May 1999

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Molecular and Cellular Endocrinology

28 July 2017

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28 July 2017

151

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28 July 2017

1-2

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28 July 2017

79-87

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

28 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Development of recombinant human prolactin receptor antagonists by molecular mimicry of the phosphorylated hormone.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Prolactin as an autocrine/paracrine factor in breast tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

STATs and gene regulation

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Activation of raf-1, MEK, and MAP kinase in prolactin responsive mammary cells

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Prolactin as a mitogen in mammary cells

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

The transcription factor Pit-1/GHF-1 is expressed in hemopoietic and lymphoid tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Pit-1/GHF-1 expression in pituitary adenomas: further analogy between human adenomas and rat SMtTW tumours.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

The 16K Fragment of Prolactin Specifically Inhibits Basal or Fibroblast Growth Factor Stimulated Growth of Capillary Endothelial Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Rational design of potent antagonists to the human growth hormone receptor

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Neovascularization induced by intraocular xenografts of normal, preneoplastic, and neoplastic mouse mammary tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassay

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

The prolactin/growth hormone receptor family: structure/function relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

1 reference

7 January 2021

Novel recombinant analogues of bovine placental lactogen. G133K and G133R provide a tool to understand the difference between the action of prolactin and growth hormone receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Jaks and Stats in signaling by the cytokine receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Insulin Receptor Substrate-1 is the Predominant Signaling Molecule Activated by Insulin-like Growth Factor-I, Insulin, and Interleukin-4 in Estrogen Receptor-positive Human Breast Cancer Cells

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

William L. McGuire Memorial Symposium. Estrogen and progestin effects in human breast carcinogenesis

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Proline-rich sequence-mediated Jak2 association to the prolactin receptor is required but not sufficient for signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Angiogenic potential of malignant and non-malignant human breast tissues in an in vivo angiogenesis model

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

8th San Antonio Breast Cancer Symposium--Plenary lecture. Autocrine and paracrine growth regulation of human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Physiological concentrations of prolactin can promote the growth of human breast tumor cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Endocrine effects of combined somatostatin analog and bromocriptine therapy in women with advanced breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Cellular expression of growth hormone and prolactin receptors in human breast disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Tyrphostin AG 494 blocks Cdk2 activation

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Is tamoxifen effective in prevention of breast cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: promoter usage and alternative mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Prolactin: the forgotten hormone of human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Binding in the growth hormone receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900023-4

7 January 2021

10.1016/S0303-7207(99)00023-4

Identifiers

DOI

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28 July 2017

1 reference