Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution (Q33694783)

28 July 2017

Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: a chemical chaperone at atomic resolution (English)

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28 July 2017

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2

Valerie Daggett

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28 July 2017

Brian J Bennion

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PubMed ID

15096583

28 July 2017

language of work or name

English

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publication date

19 April 2004

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28 July 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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28 July 2017

101

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28 July 2017

17

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28 July 2017

6433-6438

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Water and urea interactions with the native and unfolded forms of a beta-barrel protein

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

The molecular basis for the chemical denaturation of proteins by urea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Thermal and urea-induced unfolding of the marginally stable lac repressor DNA-binding domain: a model system for analysis of solute effects on protein processes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Thermodynamic binding and site occupancy in the light of the Schellman exchange concept

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Unusual organic osmolytes in deep-sea animals: adaptations to hydrostatic pressure and other perturbants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Protein-solvent preferential interactions, protein hydration, and the modulation of biochemical reactions by solvent components

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Protein folding and unfolding at atomic resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

The molecular mechanism of stabilization of proteins by TMAO and its ability to counteract the effects of urea

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Thermodynamics of interactions of urea and guanidinium salts with protein surface: relationship between solute effects on protein processes and changes in water-accessible surface area

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Protein folding from a highly disordered denatured state: the folding pathway of chymotrypsin inhibitor 2 at atomic resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Trimethylamine oxide counteracts effects of hydrostatic pressure on proteins of deep-sea teleosts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Trimethylamine oxide stabilizes teleost and mammalian lactate dehydrogenases against inactivation by hydrostatic pressure and trypsinolysis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Synergy between simulation and experiment in describing the energy landscape of protein folding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Trimethylamine-N-oxide counteracts urea effects on rabbit muscle lactate dehydrogenase function: a test of the counteraction hypothesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Time-dependent effects of trimethylamine-N-oxide/urea on lactate dehydrogenase activity: an unexplored dimension of the adaptation paradigm

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

A naturally occurring protective system in urea-rich cells: mechanism of osmolyte protection of proteins against urea denaturation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

The thermodynamic mechanism of protein stabilization by trehalose

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Temperature dependence of the preferential interactions of ribonuclease A in aqueous co-solvent systems: thermodynamic analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Mechanism of the stabilization of ribonuclease A by sorbitol: preferential hydration is greater for the denatured then for the native protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Chemical chaperones interfere with the formation of scrapie prion protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Effect of proline on lactate dehydrogenase activity: testing the generality and scope of the compatibility paradigm

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

On the role of surface tension in the stabilization of globular proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Identification and characterization of the unfolding transition state of chymotrypsin inhibitor 2 by molecular dynamics simulations.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Characterization of the transition state of protein unfolding by use of molecular dynamics: chymotrypsin inhibitor 2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Living with water stress: evolution of osmolyte systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Counteracting effects of urea and betaine in mammalian cells in culture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Counteraction of urea destabilization of protein structure by methylamine osmoregulatory compounds of elasmobranch fishes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Fifty years of solvent denaturation.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308633101

A simple model for solvation in mixed solvents. Applications to the stabilization and destabilization of macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308633101

The enthalpy of transfer of unfolded proteins into solutions of urea and guanidinium chloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308633101

Structure of the transition state for folding of a protein derived from experiment and simulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308633101

Increasing temperature accelerates protein unfolding without changing the pathway of unfolding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308633101

A microscopic view of peptide and protein solvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308633101

Generalized derivation of an exact relationship linking different coefficients that characterize thermodynamic effects of preferential interactions

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Control of protein stability and reactions by weakly interacting cosolvents: the simplicity of the complicated.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404062

Selective binding and solvent denaturation

30 October 2018

1 reference

12 December 2020

Why do some organisms use a urea-methylamine mixture as osmolyte? Thermodynamic compensation of urea and trimethylamine N-oxide interactions with protein

1 reference

12 December 2020

Natural methylamine osmolytes, trimethylamine N-oxide and betaine, increase tau-induced polymerization of microtubules

1 reference

12 December 2020

Effects of urea and trimethylamine N-oxide on fluidity of liposomes and membranes of an elasmobranch

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0308633101

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference

PubMed ID

15096583