Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation (Q33694906)

28 July 2017

title

Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation (English)

1 reference

28 July 2017

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Stefano Gianni

2

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Alan Fersht

7

object named as

Alan R Fersht

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28 July 2017

6

Valerie Daggett

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28 July 2017

Per Jemth

1

1 reference

28 July 2017

Ryan Day

3

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28 July 2017

Bin Li

4

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28 July 2017

Christopher M Johnson

5

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28 July 2017

language of work or name

English

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publication date

19 April 2004

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Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

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28 July 2017

volume

101

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28 July 2017

issue

17

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28 July 2017

page(s)

6450-6455

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Unifying features in protein-folding mechanisms

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Exploring the cytochrome c folding mechanism: cytochrome c552 from thermus thermophilus folds through an on-pathway intermediate

21 June 2018

1 reference

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The present view of the mechanism of protein folding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

The complete folding pathway of a protein from nanoseconds to microseconds

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Evidence for sequential barriers and obligatory intermediates in apparent two-state protein folding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

The structure of an FF domain from human HYPA/FBP11

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Is protein folding hierarchic? II. Folding intermediates and transition states

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Kinetic evidence for an on-pathway intermediate in the folding of cytochrome c.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

A continuous-flow capillary mixing method to monitor reactions on the microsecond time scale.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Protein folding dynamics: the diffusion-collision model and experimental data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Characterization of the transition state of protein unfolding by use of molecular dynamics: chymotrypsin inhibitor 2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

21 June 2018

1 reference

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How the molten globule became

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

Fast and slow intermediate accumulation and the initial barrier mechanism in protein folding

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401732101

Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401732101

Molecular dynamics simulation of the unfolding of barnase: characterization of the major intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401732101

Im7 folding mechanism: misfolding on a path to the native state

21 January 2018

1 reference

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Step-wise mutation of barnase to binase. A procedure for engineering increased stability of proteins and an experimental analysis of the evolution of protein stability

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=404065

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

30 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401732101

Evidence for barrier-limited protein folding kinetics on the microsecond time scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401732101

Three-state model for lysozyme folding: triangular folding mechanism with an energetically trapped intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401732101

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0401732101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0401732101

1 reference

28 July 2017

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1 reference

28 July 2017

1 reference