Antibacterial activities and inhibitory effects of sitafloxacin (DU-6859a) and its optical isomers against type II topoisomerases. (Q33696363)

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11 November 2019

title

Antibacterial activities and inhibitory effects of sitafloxacin (DU-6859a) and its optical isomers against type II topoisomerases (English)

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11 November 2019

author name string

Akasaka T

1

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11 November 2019

Kurosaka S

2

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11 November 2019

Uchida Y

3

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11 November 2019

Tanaka M

4

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11 November 2019

Sato K

5

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11 November 2019

Hayakawa I

6

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11 November 2019

language of work or name

English

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publication date

1 May 1998

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11 November 2019

number of pages

4

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Antimicrobial Agents and Chemotherapy

inferred from page(s)

published in

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11 November 2019

volume

42

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11 November 2019

issue

5

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11 November 2019

page(s)

1284-1287

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Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV purified from Staphylococcus aureus

11 November 2019

cites work

1 reference

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Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae.

14 July 2018

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ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyrase A subunit in forming resistance phenotype

14 July 2018

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Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene

14 July 2018

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Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli.

14 July 2018

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Mechanism of differential activities of ofloxacin enantiomers

14 July 2018

1 reference

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In vitro antibacterial activity of DU-6859a, a new fluoroquinolone

14 July 2018

1 reference

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Mechanism of action of quinolones against Escherichia coli DNA gyrase

14 July 2018

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Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition

14 July 2018

1 reference

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The twisted 'life' of DNA in the cell: bacterial topoisomerases

14 July 2018

1 reference

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Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus

14 July 2018

1 reference

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14 July 2018

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Biology of bacterial deoxyribonucleic acid topoisomerases

14 July 2018

1 reference

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Tandem regions of yeast DNA topoisomerase II share homology with different subunits of bacterial gyrase.

14 July 2018

1 reference

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Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymus

14 July 2018

1 reference

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New topoisomerase essential for chromosome segregation in E. coli

14 July 2018

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Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerases

14 July 2018

1 reference

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Inhibitory Effects of Quinolones on Murine Hematopoietic Progenitor Cells and Eukaryotic Topoisomerase II

14 July 2018

1 reference

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Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage.

14 July 2018

1 reference

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Antimicrobial activity of DU-6859, a new potent fluoroquinolone, against clinical isolates

14 July 2018

1 reference

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Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

14 July 2018

1 reference

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DNA gyrase: an enzyme that introduces superhelical turns into DNA

14 July 2018

1 reference

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Effect of growth conditions on antimicrobial activity of DU-6859a and its bactericidal activity determined by the killing curve method.

14 July 2018

1 reference

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Fluorocyclopropyl quinolones. 1. Synthesis and structure-activity relationships of 1-(2-fluorocyclopropyl)-3-pyridonecarboxylic acid antibacterial agents.

30 October 2018

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Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones

30 October 2018

1 reference

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Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates

30 October 2018

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Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes

30 October 2018

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12 December 2020

Mechanism of inhibition of DNA gyrase by quinolone antibacterials: specificity and cooperativity of drug binding to DNA

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12 December 2020

Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug--DNA binding model

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12 December 2020

(Fluorocyclopropyl)quinolones. 2. Synthesis and Stereochemical structure-activity relationships of chiral 7-(7-amino-5-azaspiro[2.4]heptan-5-yl)-1-(2-fluorocyclopropyl)quinolone antibacterial agents

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Identifiers

DOI

10.1128/AAC.42.5.1284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9593169%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

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11 November 2019

PubMed publication ID

9593169

1 reference