Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects (Q33698593)

24799433

28 July 2017

title

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects (English)

1 reference

28 July 2017

7

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Wei Zheng

10

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1 June 2020

Jason Hoskins

1

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1 June 2020

Amit Kumar

4

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1 June 2020

Krzysztof Sobczak

5

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1 June 2020

Masayuki Nakamori

6

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1 June 2020

Benjamin L. Miller

13

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1 June 2020

9

Juan J Marugan

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1 June 2020

8

Samarjit Patnaik

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1 June 2020

12

Matthew D Disney

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1 June 2020

author name string

Leslie O Ofori

2

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1 June 2020

Catherine Z Chen

3

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1 June 2020

Charles A Thornton

14

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1 June 2020

Christopher P Austin

11

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1 June 2020

language of work or name

English

0 references

publication date

5 May 2014

1 reference

24799433

28 July 2017

number of pages

12

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inferred from page(s)

published in

Nucleic Acids Research

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1 June 2020

volume

42

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1 June 2020

issue

10

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1 June 2020

page(s)

6591-6602

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Creative Commons Attribution 3.0 Unported

1 June 2020

copyright license

start time

10 November 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4041448/fullTextXML

inferred from PubMed Central ID database lookup

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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A detergent-based assay for the detection of promiscuous inhibitors

21 June 2018

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21 June 2018

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Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

21 June 2018

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The structural basis of myotonic dystrophy from the crystal structure of CUG repeats

21 June 2018

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Muscleblind proteins regulate alternative splicing

21 June 2018

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21 June 2018

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21 June 2018

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Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

21 June 2018

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Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR

21 June 2018

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21 June 2018

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Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts

21 June 2018

1 reference

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Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues

21 June 2018

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Lomofungin, a New Antibiotic Produced by Streptomyces lomondensis sp. n

21 June 2018

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21 June 2018

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Context dependence of hydrogen bond free energy revealed by substitutions in an RNA hairpin

21 June 2018

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Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.

21 June 2018

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Aggregating behavior of phenolic compounds--a source of false bioassay results?

21 June 2018

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30 October 2018

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12 December 2020

Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat

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Targeting RNA with Small Molecules

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Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

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Targeting RNA with small molecules

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CUG repeats present in myotonin kinase RNA form metastable "slippery" hairpins

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Identifiers

DOI

10.1093/NAR/GKU275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24799433%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24799433%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

24799433

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24799433%20AND%20SRC:MED&resulttype=core&format=json