Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3. (Q33701730)

28 July 2017

Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3. (English)

1 reference

28 July 2017

4

Alexandre M J J Bonvin

1 reference

28 July 2017

Ezgi Karaca

3

0 references

Annalisa Pastore

series ordinal

6

object named as

Annalisa Pastore

1 reference

28 July 2017

Sokol V Todi

2

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author name string

Giuseppe Nicastro

series ordinal

1

1 reference

PubMed ID

20865150

28 July 2017

Henry L Paulson

series ordinal

5

1 reference

PubMed ID

20865150

28 July 2017

language of work or name

English

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publication date

26 August 2010

1 reference

28 July 2017

1 reference

28 July 2017

5

1 reference

28 July 2017

8

1 reference

28 July 2017

e12430

1 reference

Creative Commons Attribution 4.0 International

28 July 2017

start time

26 August 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3.

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The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.

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Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity

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The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition

14 July 2018

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14 July 2018

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A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.

14 July 2018

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The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity

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14 July 2018

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14 July 2018

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14 July 2018

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Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites.

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The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step.

21 January 2018

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Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

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Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3

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Assignment of the 1H, 13C, and 15N resonances of the Josephin domain of human ataxin-3

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Regulated protein degradation

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Identifiers

DOI

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference

PubMed ID

20865150