Cell-based and animal models for hepatitis B and C viruses (Q33702348)

28 July 2017

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title

Cell-based and animal models for hepatitis B and C viruses (English)

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28 July 2017

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R F Schinazi

1

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28 July 2017

E Ilan

2

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28 July 2017

P L Black

3

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28 July 2017

X Yao

4

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28 July 2017

S Dagan

5

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28 July 2017

1 May 1999

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Antiviral Chemistry & Chemotherapy

28 July 2017

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28 July 2017

10

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28 July 2017

3

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28 July 2017

99-114

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Transmissible agent in non-A, non-B hepatitis

28 July 2017

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The human bone-marrow-derived B-cell line CE, susceptible to hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

A severe combined immunodeficiency mutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Experimental infection of chimpanzees with antihemophilic (factor viii) materials: Recovery of virus-like particles associated with non-A, non-B hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Posttransfusion non-A, non-B hepatitis: physicochemical properties of two distinct agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Non-A, Non-B Hepatitis: Toward the Discovery of Hepatitis C and E Viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

HBV and HDV replication in experimental models: effect of interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Synthesis and biological evaluation of a series of 2'-fluorinated-2',3'-dideoxy-2',3'-didehydro-(L)-nucleosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

In vitro infection of peripheral blood mononuclear cells by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis C viral RNA in serum of patients with chronic non-A, non-B hepatitis: detection by the polymerase chain reaction using multiple primer sets

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Effect of beta-enantiomeric and racemic nucleoside analogues on mitochondrial functions in HepG2 cells. Implications for predicting drug hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Treatment of chronic hepatitis C with recombinant interferon alfa. A multicenter randomized, controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Reversion of duck hepatitis B virus DNA replication in vivo following cessation of treatment with the nucleoside analogue ganciclovir

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Aspergillus wound infection following laparostomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Production and immunological analysis of recombinant hepatitis B vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Human monoclonal antibodies specific to hepatitis B virus generated in a human/mouse radiation chimera: the Trimera system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

A long-term study of hepatitis C virus replication in non-A, non-B hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Inhibition of hepatitis B virus surface antigen gene expression in carcinogen-induced liver tumors from transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Transfusion-Associated Hepatitis Not Due to Viral Hepatitis Type A or B

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Non-A, non-B hepatitis in chimpanzees and marmosets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis C virus viremia in SCID-->BNX mouse chimera

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The molecular biology of the hepatitis B viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Pre- and postexposure protection against human immunodeficiency virus type 1 infection mediated by a monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

To kill or to cure: options in host defense against viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Comparison of properties of woodchuck hepatitis virus and human hepatitis B virus endogenous DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Determining the size of non-A, non-B hepatitis virus by filtration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Non-A, non-B hepatitis transmission in chimpanzees: a project of the transfusion-transmitted viruses study group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Therapy of chronic type B hepatitis with adenine arabinoside and adenine arabinoside monophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Replication and multiplication of hepatitis C virus genome in human foetal liver cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Analysis of the cell tropism of HCV by using in vitro HCV-infected human lymphocytes and hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The hepatitis B virus-trimera mouse: a model for human HBV infection and evaluation of anti-HBV therapeutic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Cultivation of hepatitis C virus in primary hepatocyte culture from patients with chronic hepatitis C results in release of high titre infectious virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Neutralization of hepatitis B virus infectivity by a murine monoclonal antibody: an experimental study in the chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Experimental infection of Tamarins with human non-A, non-B hepatitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Replication of hepatitis C virus in cultured non-neoplastic human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Transgenic expression of hepatitis C virus structural proteins in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

L-beta-(2S,4S)- and L-alpha-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Evolution at two levels in humans and chimpanzees

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Demonstration of in vitro infection of chimpanzee hepatocytes with hepatitis C virus using strand-specific RT/PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Natural populations of woodchuck hepatitis virus contain variant precore and core sequences including a premature stop codon in the epsilon motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The SCID-hu mouse: a small animal model for HIV infection and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Experimental transmission of duck hepatitis B virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

An open letter to the FDA regarding changes in reporting procedures for drugs and biologics proposed in the wake of the FIAU tragedy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Long-term human T-cell culture system supporting hepatitis C virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Positional isomers of monopegylated interferon alpha-2a: isolation, characterization, and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Continuous human cell lines inducibly expressing hepatitis C virus structural and nonstructural proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis C virus core protein induces hepatic steatosis in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Rapid loss of CD4+ T cells in human-PBL-SCID mice by noncytopathic HIV isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Demonstration of duck hepatitis B virus in bile duct epithelial cells: implications for pathogenesis and persistent infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The use of ampligen alone and in combination with ganciclovir and coumermycin A1 for the treatment of ducks congenitally-infected with duck hepatitis B virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Markedly prolonged incubation period of hepatitis B in a chimpanzee passively immunized with a human monoclonal antibody to the a determinant of hepatitis B surface antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Detection of hepatitis B and woodchuck hepatitis viral DNA in plasma and mononuclear cells from heparinized blood by the polymerase chain reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis C virus core and E2 protein expression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Binding of hepatitis C virus to CD81

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Inhibition of the replication of hepatitis B virus by the carbocyclic analogue of 2'-deoxyguanosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis B virus, hepatitis non-A, non-B virus and hepatitis delta virus in lyophilized antihemophilic factor: relative sensitivity to heat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis viruses: changing patterns of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis C viral RNA titers in serum prior to, during, and after oral treatment with ribavirin for chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The Trimera mouse: generating human monoclonal antibodies and an animal model for human diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The woodchuck: an animal model for hepatitis B virus infection in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Inhibition of human and duck hepatitis B virus by 2',3'-dideoxy-3'-fluoroguanosine in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Establishment of persistent hepatitis C virus infection and replication in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Early events in hepatitis C virus infection of chimpanzees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

The in vitro anti-hepatitis B virus activity of FIAU [1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl-5-iodo)uracil] is selective, reversible, and determined, at least in part, by the host cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Inactivation of an agent of human non-A, non-B hepatitis by formalin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Transmission of non-A, non-B hepatitis from man to chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Acquired Immunity to Human Non-A, Non-B Hepatitis: Cross-Challenge of Chimpanzees with Three Infectious Human Sera

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Acute hepatitis in rats expressing human hepatitis B virus transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

New human hepatitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Hepatitis C virus infection of a Vero cell clone displaying efficient virus-cell binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Transmission of non-A non-B hepatitis to chimpanzees by factor-IX concentrates after fatal complications in patients with chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Human hepatitis B virus and hepatocellular carcinoma I. Experimental infection of tree shrews with hepatitis B virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

Human hepatitis B virus and hepatocellular carcinoma. II. Experimental induction of hepatocellular carcinoma in tree shrews exposed to hepatitis B virus and aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

In vivo inhibition of hepatitis B viral gene expression by antisense phosphorothioate oligodeoxynucleotides in athymic nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632029901000301

10.1177/095632029901000301

21 January 2018

Identifiers

DOI

1 reference

28 July 2017

1 reference