Entacapone. A review of its use in Parkinson's disease (Q33706744)

28 July 2017

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title

Entacapone. A review of its use in Parkinson's disease (English)

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28 July 2017

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K J Holm

1

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PubMed ID

10439935

28 July 2017

C M Spencer

series ordinal

2

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28 July 2017

1 July 1999

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28 July 2017

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28 July 2017

58

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28 July 2017

1

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28 July 2017

159-177

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https://scigraph.springernature.com/pub.10.2165/00003495-199958010-00017

28 July 2017

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Effect of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, on the motor response to acute treatment with levodopa in patients with Parkinson's disease

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Simultaneous inhibition of catechol-O-methyltransferase and monoamine oxidase A: effects on hemodynamics and catecholamine metabolism in healthy volunteers

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Entacapone enhances levodopa-induced reversal of motor disability in MPTP-treated common marmosets

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Entacapone, a novel catechol-O-methyltransferase inhibitor for Parkinson's disease, does not impair mitochondrial energy production

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Management of motor fluctuations in Parkinson's disease

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Entacapone prolongs levodopa response in a one month double blind study in parkinsonian patients with levodopa related fluctuations

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Effect of one month's treatment with peripherally acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients.

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A double-blind pharmacokinetic and clinical dose-response study of entacapone as an adjuvant to levodopa therapy in advanced Parkinson's disease

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The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers

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Extending levodopa action: COMT inhibition

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Catechol-O-methyltransferase: variation in enzyme activity and inhibition by entacapone and tolcapone.

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New pharmacotherapy for Parkinson's disease

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Identification of major metabolites of the catechol-O-methyltransferase inhibitor entacapone in rats and humans

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Effect of entacapone, a COMT inhibitor, on clinical disability and levodopa metabolism in parkinsonian patients

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The effect of entacapone on the disposition and hemodynamic effects of intravenous isoproterenol and epinephrine

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Simultaneous inhibition of catecholamine-O-methylation by entacapone and neuronal uptake by imipramine: lack of interactions

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COMT inhibition by entacapone does not affect growth hormone or prolactin secretion in healthy volunteers

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12 December 2020

10.2165/00003495-199958010-00017

Identifiers

DOI

1 reference

PubMed ID

10439935

Dimensions Publication ID

28 July 2017

0 references

1 reference

PubMed ID

10439935