Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases (Q33707101)

28 July 2017

title

Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases (English)

1 reference

28 July 2017

Qingming Fang

1

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John A. Tainer

object named as

John A Tainer

4

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author name string

Sreenivas Kanugula

2

1 reference

28 July 2017

Julie L Tubbs

3

1 reference

28 July 2017

Anthony E Pegg

5

1 reference

28 July 2017

language of work or name

English

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publication date

21 December 2009

1 reference

Journal of Biological Chemistry

28 July 2017

published in

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28 July 2017

volume

285

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28 July 2017

issue

11

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28 July 2017

page(s)

8185-8195

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describes a project that uses

28 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2832970/fullTextXML

inferred from PubMed Central ID database lookup

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis

21 June 2018

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Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair

21 June 2018

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Comparison of the relative mutagenicities of O-alkylthymines site-specifically incorporated into phi X174 DNA.

21 June 2018

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Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides

21 June 2018

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Repair of O6-methylguanine, O6-ethylguanine, O6-isopropylguanine and O4-methylthymine in synthetic oligodeoxynucleotides by Escherichia coli ada gene O6-alkylguanine-DNA-alkyltransferase

21 June 2018

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21 June 2018

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A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions

21 June 2018

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21 June 2018

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Site-specifically alkylated oligodeoxynucleotides: probes for mutagenesis, DNA repair and the structural effects of DNA damage

21 June 2018

1 reference

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Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

21 June 2018

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Comparative efficiency of forming m4T.G versus m4T.A base pairs at a unique site by use of Escherichia coli DNA polymerase I (Klenow fragment) and Drosophila melanogaster polymerase alpha-primase complex

21 June 2018

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Comparative mutagenesis of O6-methylguanine and O4-methylthymine in Escherichia coli.

21 June 2018

1 reference

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21 June 2018

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Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse.

21 June 2018

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Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases

21 June 2018

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Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes

21 June 2018

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Efficient repair of O6-ethylguanine, but not O4-ethylthymine or O2-ethylthymine, is dependent upon O6-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832970

Comparison of mutagenesis by O6-methyl- and O6-ethylguanine and O4-methylthymine in Escherichia coli using double-stranded and gapped plasmids

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.045518

Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.045518

Mammalian DNA repair methyltransferases shield O4MeT from nucleotide excision repair.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.045518

Mouse methyltransferase for repair of O6-methylguanine and O4-methylthymine in DNA.

21 January 2018

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DNA binding and nucleotide flipping by the human DNA repair protein AGT.

21 January 2018

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The structure of the human AGT protein bound to DNA and its implications for damage detection

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.045518

O6-alkylguanine-DNA alkyltransferase: low pKa and high reactivity of cysteine 145.

21 January 2018

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Enhanced in vivo repair of O(4)-methylthymine by a mutant human DNA alkyltransferase.

21 January 2018

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Function of domains of human O6-alkylguanine-DNA alkyltransferase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.045518

Repair of oligodeoxyribonucleotides by O(6)-alkylguanine-DNA alkyltransferase.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.045518

Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase.

21 January 2018

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ESyPred3D: Prediction of proteins 3D structures

21 January 2018

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CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

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Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.

21 January 2018

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Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells

21 January 2018

1 reference

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Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance

21 January 2018

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The alkyltransferase-like ybaZ gene product enhances nucleotide excision repair of O(6)-alkylguanine adducts in E. coli

21 January 2018

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Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide

21 January 2018

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30 October 2018

A magnificence to share

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DNA binding mechanism of O6-alkylguanine-DNA alkyltransferase: stoichiometry and effects of DNA base composition and secondary structure on complex stability

21 January 2018

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12 December 2020

Repair of O6-benzylguanine by the Escherichia coli Ada and Ogt and the human O6-alkylguanine-DNA alkyltransferases

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12 December 2020

Repair of O6-methylguanine and O4-methylthymidine in F344 rat liver following treatment with 1,2-dimethylhydrazine and O6-benzylguanine

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12 December 2020

Flexibility and curvature of DNA duplexes containing O4-methylthymine: implications for DNA repair

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12 December 2020

Identifiers

DOI

10.1074/JBC.M109.045518

1 reference

28 July 2017

1 reference

28 July 2017

1 reference