Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells (Q33707814)

28 July 2017

title

Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells (English)

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28 July 2017

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Sykes M

1

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28 July 2017

Romick ML

series ordinal

2

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28 July 2017

Sachs DH

series ordinal

3

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28 July 2017

language of work or name

English

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publication date

1 August 1990

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Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

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28 July 2017

volume

87

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28 July 2017

issue

15

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28 July 2017

page(s)

5633-5637

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Studies in antibody response of mice to tumour inoculation

28 July 2017

cites work

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Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2.

21 June 2018

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Analysis of the murine lymphokine-activated killer (LAK) cell phenomenon: dissection of effectors and progenitors into NK- and T-like cells.

21 June 2018

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21 June 2018

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Toxicity of human recombinant interleukin-2 in the mouse is mediated by interleukin-activated lymphocytes. Separation of efficacy and toxicity by selective lymphocyte subset depletion

21 June 2018

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Heterogeneity of lymphokine-activated killer cells induced by IL-2. Separate lymphoid subpopulations lyse tumor, allogeneic blasts, and modified syngeneic blasts

21 June 2018

1 reference

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In vivo induction of the lymphokine-activated killer phenomenon: interleukin 2-dependent human non-major histocompatibility complex-restricted cytotoxicity generated in vivo during administration of human recombinant interleukin 2.

21 June 2018

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Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance.

21 June 2018

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Effect of selective T cell depletion of host and/or donor bone marrow on lymphopoietic repopulation, tolerance, and graft-vs-host disease in mixed allogeneic chimeras (B10 + B10.D2----B10).

21 June 2018

1 reference

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In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment

21 June 2018

1 reference

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Monoclonal anti-H-2Kb antibodies detect serological differences betweenH-2K b mutants

21 June 2018

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12 December 2020

Systemic administration of recombinant human interleukin-2 in mice

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12 December 2020

Graft rejection in recipients of T-cell-depleted HLA-nonidentical marrow transplants for leukemia. Identification of host-derived antidonor allocytotoxic T lymphocytes

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12 December 2020

Effects of T cell depletion in radiation bone marrow chimeras. I. Evidence for a donor cell population which increases allogeneic chimerism but which lacks the potential to produce GVHD

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12 December 2020

Adoptive immunotherapy in conjunction with bone marrow transplantation--amplification of natural host defence mechanisms against cancer by recombinant IL-2

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12 December 2020

Graft failure in patients receiving T cell-depleted HLA-identical allogeneic marrow transplants

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12 December 2020

Evidence for tumor reduction in refractory or relapsed B-CLL patients with infusional interleukin-2

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12 December 2020

Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

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12 December 2020

Genetic analysis of the anti-leukemic effect of mixed allogeneic bone marrow transplantation

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12 December 2020

Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia

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12 December 2020

Graft-versus-leukemia effect using mixed allogeneic bone marrow transplantation

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12 December 2020

Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patients

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12 December 2020

Effects of T cell depletion in radiation bone marrow chimeras. III. Characterization of allogeneic bone marrow cell populations that increase allogeneic chimerism independently of graft-vs-host disease in mixed marrow recipients

1 reference

12 December 2020

Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic marrow transplantation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.87.15.5633

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28 July 2017

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28 July 2017

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