Extracellular modulation of the Hedgehog, Wnt and TGF-beta signalling pathways during embryonic development (Q33712582)

28 July 2017

1 reference

title

Extracellular modulation of the Hedgehog, Wnt and TGF-beta signalling pathways during embryonic development (English)

1 reference

28 July 2017

Capdevila J

1

1 reference

PubMed ID

10449357

28 July 2017

lzpisúa Belmonte JC

series ordinal

2

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28 July 2017

1 August 1999

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Current Opinion in Genetics & Development

28 July 2017

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28 July 2017

9

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28 July 2017

4

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28 July 2017

427-433

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Morphogens, compartments, and pattern: lessons from drosophila?

28 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Transducing Hedgehog: the story so far

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

New players and puzzles in the Hedgehog signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Mechanisms of Wnt signaling in development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Wnt signaling: why is everything so negative?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Cellular mechanisms of wingless/Wnt signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

BMPs, Smads and metalloproteases: extracellular and intracellular modes of negative regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

TGF-beta signaling, Smads, and tumor suppressors.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

The Drosophila patched gene encodes a putative membrane protein required for segmental patterning

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Biochemical evidence that patched is the Hedgehog receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Dual roles for patched in sequestering and transducing Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Expression and functional analysis of mouse EXT1, a homolog of the human multiple exostoses type 1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Cholesterol modification of hedgehog signaling proteins in animal development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Identification of a palmitic acid-modified form of human Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Functional rafts in cell membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Functions of lipid rafts in biological membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

A new member of the frizzled family from Drosophila functions as a Wingless receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Fritz: a secreted frizzled-related protein that inhibits Wnt activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Frzb-1, an antagonist of Wnt-1 and Wnt-8, does not block signaling by Wnts -3A, -5A, or -11.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

sFRP-2 is a target of the Wnt-4 signaling pathway in the developing metanephric kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

A colipase fold in the carboxy-terminal domain of the Wnt antagonists--the Dickkopfs.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

A new secreted protein that binds to Wnt proteins and inhibits their activities

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Bone morphogenetic proteins in development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two type I receptors, SAX and TKV.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

TGF beta inhibitors. New and unexpected requirements in vertebrate development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Neural induction by the secreted polypeptide noggin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Antagonism within and around the organizer: BMP inhibitors in vertebrate body patterning

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

A product of DAN, a novel candidate tumour suppressor gene, is secreted into culture medium and suppresses DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

DAN is a secreted glycoprotein related to Xenopus cerberus.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Murine cerberus homologue mCer-1: a candidate anterior patterning molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

A mouse cerberus/Dan-related gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Mesoderm induction by BMP-4 and -7 heterodimers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Ventral mesoderm induction and patterning by bone morphogenetic protein heterodimers in Xenopus embryos.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Local inhibition and long-range enhancement of Dpp signal transduction by Sog.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Cleavage of the BMP-4 antagonist chordin by zebrafish tolloid

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Developmental biology. A unity of opposites.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

Negative feedback mechanisms and their roles during pattern formation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980065-3

7 January 2021

10.1016/S0959-437X(99)80065-3

Identifiers

DOI

1 reference

28 July 2017

1 reference

PubMed ID

10449357