Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein. (Q33713319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10450515%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

review article

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title

Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein (English)

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11 December 2019

1

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11 December 2019

author name string

Goverman J

series ordinal

1

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28 July 2017

publication date

1 June 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10450515%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

published in

Immunological Reviews

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11 December 2019

volume

169

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11 December 2019

page(s)

147-159

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A population-based study of multiple sclerosis in twins: update

11 December 2019

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Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells

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Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

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Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

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Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production

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Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

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Low avidity recognition of self-antigen by T cells permits escape from central tolerance.

21 January 2018

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21 January 2018

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Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein

21 January 2018

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Endogenous myelin basic protein inactivates the high avidity T cell repertoire

21 January 2018

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21 January 2018

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21 January 2018

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T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

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21 January 2018

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Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

21 January 2018

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Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis

21 January 2018

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Elicitation of experimental allergic encephalomyelitis (EAE) in mice with the aid of pertussigen

21 January 2018

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High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

21 January 2018

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TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines

21 January 2018

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Interleukin-10 prevents experimental allergic encephalomyelitis in rats.

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Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse

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Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice.

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The increased susceptibility of women to multiple sclerosis

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Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death. A model for T-cell apoptosis in vivo

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Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity

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12 December 2020

Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice

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Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor

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Peripheral deletion of antigen-reactive T cells in oral tolerance.

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12 December 2020

Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells

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Vaccination against experimental allergic encephalomyelitis with T cell receptor peptides

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Homing to central nervous system vasculature by antigen-specific lymphocytes. II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination

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Vaccination with BV8S2 protein amplifies TCR-specific regulation and protection against experimental autoimmune encephalomyelitis in TCR BV8S2 transgenic mice

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Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes

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A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire

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12 December 2020

Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle.

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Highly cross-reactive T cell responses to myelin basic protein epitopes reveal a nonpredictable form of TCR degeneracy

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Interaction of T Lymphocytes with Cerebral Endothelial Cells in vitro

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Relapsing experimental allergic encephalomyelitis in the SJL/J mouse

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T cell determinant structure of myelin basic protein in B10.PL, SJL/J, and their F1S.

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Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice

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Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta

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Myelin basic protein peptide complexes with the class II MHC molecules I-Au and I-Ak form and dissociate rapidly at neutral pH.

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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Myelin basic protein-specific and TCR V beta 8.2-specific T-cell lines from TCR V beta 8.2 transgenic mice utilize the same V alpha and V beta genes: specificity associated with the V alpha CDR3-J alpha region

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Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse

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An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction

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Abrogation of resistance to Theiler's virus-induced demyelination in H-2b mice deficient in beta 2-microglobulin

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Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats

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Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis

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The T lymphocyte in experimental allergic encephalomyelitis

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Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

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Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis

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Apoptotic elimination of V beta 8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of V beta 8.2+ encephalitogenic T cells

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An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis

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Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity

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T cell receptor peptide therapy triggers autoregulation of experimental encephalomyelitis

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T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

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12 December 2020

10.1111/J.1600-065X.1999.TB01313.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10450515%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

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