Achieving an optimal outcome in the treatment of infections. The role of clinical pharmacokinetics and pharmacodynamics of antimicrobials (Q33714230)

28 July 2017

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title

Achieving an optimal outcome in the treatment of infections. The role of clinical pharmacokinetics and pharmacodynamics of antimicrobials (English)

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ORCID Public Data File 2021

28 July 2017

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author name string

Li RC

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1

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28 July 2017

Zhu M

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2

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28 July 2017

Schentag JJ

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3

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28 July 2017

language of work or name

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1 July 1999

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Clinical Pharmacokinetics

28 July 2017

published in

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28 July 2017

volume

37

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28 July 2017

issue

1

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28 July 2017

page(s)

1-16

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Once versus thrice daily gentamicin in patients with serious infections

28 July 2017

cites work

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Mathematical Examination of Dual Individualization Principles (I): Relationships between AUC above MIC and Area under the Inhibitory Curve for Cefmenoxime, Ciprofloxacin, and Tobramycin

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Impact of pharmacokinetics on the postantibiotic effect exhibited by Pseudomonas aeruginosa following tobramycin exposure: application of an in-vitro model

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Inactivation of antibiotics and the dissemination of resistance genes

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The theory and relevance of continuous culture

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Impact of dosage regimens on the efficacy of piperacillin against Pseudomonas aeruginosa in neutropenic mice

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Antibiotic tissue penetration and its relevance: impact of tissue penetration on infection response

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The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents

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Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients

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Influence of protein binding on therapeutic efficacy of cefoperazone

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Advantages and disadvantages of an in-vitro model with two compartments connected by a dialyser: results of experiments with ciprofloxacin.

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The fractional inhibitory concentration (FIC) index as a measure of synergy

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Twenty-four-hour area under the concentration-time curve/MIC ratio as a generic predictor of fluoroquinolone antimicrobial effect by using three strains of Pseudomonas aeruginosa and an in vitro pharmacodynamic model

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Mechanistic investigation of the reduction in antimicrobial activity of ciprofloxacin by metal cations.

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Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy

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Pharmacokinetics and ototoxicity of gentamicin, tobramycin, and amikacin

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Application of in-vitro models: development of resistance.

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In vitro pharmacodynamics of piperacillin, piperacillin-tazobactam, and ciprofloxacin alone and in combination against Staphylococcus aureus, Klebsiella pneumoniae, Enterobacter cloacae, and Pseudomonas aeruginosa

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In nosocomial pneumonia, optimizing antibiotics other than aminoglycosides is a more important determinant of successful clinical outcome, and a better means of avoiding resistance.

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A new approach to in vitro comparisons of antibiotics in dynamic models: equivalent area under the curve/MIC breakpoints and equiefficient doses of trovafloxacin and ciprofloxacin against bacteria of similar susceptibilities

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Correlation between bactericidal activity and postantibiotic effect for five antibiotics with different mechanisms of action.

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Bactericidal Activity of Cephalosporins in an In Vitro Model Simulating Serum Levels

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An in vitro model for monitoring bacterial responses to antibiotic agents under simulated in vivo conditions

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Relationship Between Aminoglycoside-Induced Nephrotoxicity and Auditory Toxicity

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Antibiotic kinetics and dynamics for the clinician.

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Antibiotic exposure and its relationship to postantibiotic effect and bactericidal activity: constant versus exponentially decreasing tobramycin concentrations against Pseudomonas aeruginosa

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Historical review of in-vitro models

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Simultaneous pharmacodynamic analysis of the lag and bactericidal phases exhibited by beta-lactams against Escherichia coli

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Antimicrobial resistance issues of the future

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Markedly different rates and resistance profiles exhibited by seven commonly used and newer beta-lactams on the selection of resistant variants of Enterobacter cloacae

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Differences between in vitro and in vivo studies

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12 December 2020

Mathematical examination of dual individualization principles (II): The rate of bacterial eradication at the same area under the inhibitory curve is more rapid for ciprofloxacin than for cefmenoxime.

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12 December 2020

Renal and auditory toxicity of high-dose, prolonged therapy with gentamicin and tobramycin in pseudomonas endocarditis

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Post-antibiotic effects in experimental infection models: relationship to in-vitro phenomena and to treatment of infections in man.

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Experimental efficacy of combined ceftriaxone and amoxycillin on penicillin-resistant and broad-spectrum cephalosporin-resistant Streptococcus pneumoniae infection.

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Chromosomal beta-lactamase expression and antibiotic resistance in Enterobacter cloacae

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Origin and evolution of genes specifying resistance to macrolide, lincosamide and streptogramin antibiotics: data and hypotheses

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Pharmacodynamics of amikacin in vitro and in mouse thigh and lung infections

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12 December 2020

Gentamicin blood levels: a guide to nephrotoxicity

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12 December 2020

Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model

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12 December 2020

The ability of beta-lactam antibiotics to select mutants with derepressed beta-lactamase synthesis from Citrobacter freundii

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12 December 2020

Kinetics of antimicrobial action

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12 December 2020

Artifacts in dilution pharmacokinetic models caused by adherent bacteria

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12 December 2020

Kinetics and mechanisms of action of drugs on microorganisms. VII. Quantitative adherence of sulfonamide action on microbial growth to a receptor-site model

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12 December 2020

New In Vitro Model to Study the Effect of Antibiotic Concentration and Rate of Elimination on Antibacterial Activity

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12 December 2020

Pharmacodynamic modeling of bacterial kinetics: beta-lactam antibiotics against Escherichia coli.

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12 December 2020

In vivo postantibiotic effect in a thigh infection in neutropenic mice

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12 December 2020

Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration

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12 December 2020

Evaluation of activity of temafloxacin against Bacteroides fragilis by an in vitro pharmacodynamic system

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12 December 2020

Pharmacokinetic-pharmacodynamic modeling of the antibiotic effect of piperacillin in vitro

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12 December 2020

Microbial kinetics of beta-lactam antibiotics against Escherichia coli.

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12 December 2020

Significance of Serum Protein and Tissue Binding of Antimicrobial Agents

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12 December 2020

Antimicrobial Resistance in Hospital Organisms and Its Relation to Antibiotic Use

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12 December 2020

Mathematical examination of dual individualization principles. (III): Development of a scoring system for pneumonia staging and quantitation of response to antibiotics: results in cefmenoxime-treated patients

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12 December 2020

Once-daily versus multiple-daily dosing of aminoglycosides

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12 December 2020

Kinetic analysis and characterization of the bacterial regrowth after treatment of Escherichia coli with beta-lactam antibiotics

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12 December 2020

Dual individualization of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections.

1 reference

12 December 2020

The pharmacodynamics of aminoglycosides

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12 December 2020

In-vitro model for simultaneous simulation of the serum kinetics of two drugs with different half-lives.

1 reference

12 December 2020

Microbial pharmacodynamics of piperacillin in neutropenic mice of systematic infection due to Pseudomonas aeruginosa

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12 December 2020

AUIC--the universal parameter within the constraint of a reasonable dosing interval

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12 December 2020

The fractional maximal effect method: a new way to characterize the effect of antibiotic combinations and other nonlinear pharmacodynamic interactions

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12 December 2020

Differences between bacteria grown in vitro and in vivo

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12 December 2020

Prevention of drug access to bacterial targets: permeability barriers and active efflux

1 reference

12 December 2020

The postantibiotic effect: a review of in vitro and in vivo data

1 reference

12 December 2020

Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins

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12 December 2020

Simultaneous simulation of two different concentration time curves in vitro.

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12 December 2020

Microbial Kinetics and Dependencies of Individual and Combined Antibiotic Inhibitors of Protein Biosynthesis

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12 December 2020

10.2165/00003088-199937010-00001

Identifiers

DOI

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Dimensions Publication ID

28 July 2017

1050139303

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