HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus (Q33716978)

28 July 2017

HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus (English)

1 reference

putative long-chain-fatty-acid-CoA ligase

28 July 2017

Aspergillus fumigatus

0 references

1 reference

5 February 2019

1 reference

hydroxyornithine transacylase

5 February 2019

L-ornithine N5-oxygenase

1 reference

5 February 2019

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5 February 2019

1 reference

putative siderophore transporter

6 February 2019

1 reference

Putative siderophore iron transporter

6 February 2019

1 reference

Putative acetyltransferase with a predicted role in iron metabolism

6 February 2019

1 reference

Putative heme transporter

6 February 2019

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Has domain(s) with predicted N-acetyltransferase activity

6 February 2019

1 reference

Secreted protein of unknown function

6 February 2019

1 reference

6 February 2019

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6 February 2019

bZIP transcription factor HapX

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Putative ferrochelatase precursor

6 February 2019

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GATA transcription factor that regulates iron uptake

6 February 2019

1 reference

6 February 2019

Nicola Beckmann

2

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John J Varga

John Varga

3

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Tarek A Moussa

Tarek A Moussa

7

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Thorsten Heinekamp

Thorsten Heinekamp

4

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Ilse D. Jacobsen

Ilse D Jacobsen

5

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Ernst R Werner

Ernst R Werner

11

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Axel A Brakhage

13

Axel A Brakhage

1 reference

28 July 2017

1

Markus Schrettl

1 reference

28 July 2017

14

Hubertus Haas

1 reference

28 July 2017

Christoph Jöchl

6

1 reference

28 July 2017

Shaohua Wang

8

1 reference

28 July 2017

Fabio Gsaller

9

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28 July 2017

Michael Blatzer

10

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28 July 2017

William C Niermann

12

1 reference

28 July 2017

30 September 2010

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28 July 2017

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28 July 2017

6

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28 July 2017

9

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28 July 2017

e1001124

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Creative Commons Attribution 4.0 International

28 July 2017

start time

30 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Metabolic response to iron deficiency in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

The iron chelator deferasirox enhances liposomal amphotericin B efficacy in treating murine invasive pulmonary aspergillosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Both Php4 function and subcellular localization are regulated by iron via a multistep mechanism involving the glutaredoxin Grx4 and the exportin Crm1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Ferricrocin, a siderophore involved in intra- and transcellular iron distribution in Aspergillus fumigatus.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Effects of the Aspergillus fumigatus siderophore systems on the regulation of macrophage immune effector pathways and iron homeostasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

SreA-mediated iron regulation in Aspergillus fumigatus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Siderophores in fungal physiology and virulence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Cooperation of two mRNA-binding proteins drives metabolic adaptation to iron deficiency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Histoplasma requires SID1, a member of an iron-regulated siderophore gene cluster, for host colonization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Key function for the CCAAT-binding factor Php4 to regulate gene expression in response to iron deficiency in fission yeast.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

EstB-mediated hydrolysis of the siderophore triacetylfusarinine C optimizes iron uptake of Aspergillus fumigatus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Fungal ribotoxins: molecular dissection of a family of natural killers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

A transcription factor cascade involving Fep1 and the CCAAT-binding factor Php4 regulates gene expression in response to iron deficiency in the fission yeast Schizosaccharomyces pombe

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

EDTA as an adjunct antifungal agent for invasive pulmonary aspergillosis in a rodent model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Aspergillus fumigatus: saprophyte or pathogen?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophores

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Characterization of the Aspergillus nidulans transporters for the siderophores enterobactin and triacetylfusarinine C.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Iron and immunity: a double-edged sword.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

The role of iron in protozoan and fungal infectious diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

Oxygen toxicity, oxygen radicals, transition metals and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947994

The siderophore biosynthetic gene SID1, but not the ferroxidase gene FET3, is required for full Fusarium graminearum virulence.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

NPS6, encoding a nonribosomal peptide synthetase involved in siderophore-mediated iron metabolism, is a conserved virulence determinant of plant pathogenic ascomycetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

The Aspergillus nidulans GATA factor SREA is involved in regulation of siderophore biosynthesis and control of iron uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

Immune responses of human immature dendritic cells can be modulated by the recombinant Aspergillus fumigatus antigen Aspf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

The interplay between iron and zinc metabolism in Aspergillus fumigatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

Efficient PCR-based gene targeting with a recyclable marker for Aspergillus nidulans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

Dissecting individual steps of nitrogen transcription factor cooperation in the Aspergillus nidulans nitrate cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001124

The genetics of Aspergillus nidulans

21 January 2018

1 reference

12 December 2020

Increased bone marrow iron stores is an independent risk factor for invasive aspergillosis in patients with high-risk hematologic malignancies and recipients of allogeneic hematopoietic stem cell transplantation

1 reference

12 December 2020

Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletion

1 reference

12 December 2020

A transformant of Aspergillus fumigatus deficient in the antigenic cytotoxin ASPFI

1 reference

12 December 2020

Host-dependent patterns of tissue injury in invasive pulmonary aspergillosis

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1001124

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference