Zileuton, a new efficient and safe systemic anti-acne drug (Q33716998)

28 July 2017

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title

Zileuton, a new efficient and safe systemic anti-acne drug (English)

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28 July 2017

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ChEBI release 2020-05-28

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Christos C Zouboulis

1

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28 July 2017

1 May 2009

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28 July 2017

5

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inferred from page(s)

published in

Dermato-endocrinology

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28 July 2017

1

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28 July 2017

3

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28 July 2017

188-192

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The sebocyte culture: a model to study the pathophysiology of the sebaceous gland in sebostasis, seborrhoea and acne

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Frontiers in sebaceous gland biology and pathology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Inflammatory events are involved in acne lesion initiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Differentiation and apoptosis in human immortalized sebocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Prostaglandins and leukotrienes: advances in eicosanoid biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Peroxisome proliferator-activated receptors in inflammation control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Leukotriene B4: metabolism and signal transduction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

The treatment of acne fulminans: a review of 25 cases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Chemical probes that differentially modulate peroxisome proliferator-activated receptor alpha and BLTR, nuclear and cell surface receptors for leukotriene B(4).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

The PPARalpha-leukotriene B4 pathway to inflammation control.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Oral ibuprofen and tetracycline for the treatment of acne vulgaris

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

What is the pathogenesis of acne?

21 June 2018

1 reference

https://api.crossref.org/works/10.4161%2FDERM.1.3.8368

Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FDERM.1.3.8368

A new concept for acne therapy: a pilot study with zileuton, an oral 5-lipoxygenase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FDERM.1.3.8368

Zileuton, an oral 5-lipoxygenase inhibitor, directly reduces sebum production

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FDERM.1.3.8368

Zileuton prevents the activation of the leukotriene pathway and reduces sebaceous lipogenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835912

Systemic corticosteroid and isotretinoin treatment in cystic acne

30 October 2018

1 reference

12 December 2020

5-lipoxygenase inhibitory activity of zileuton

1 reference

12 December 2020

Ligand selectivity of the peroxisome proliferator-activated receptor alpha

1 reference

12 December 2020

Mechanisms of androgen induction of sebocyte differentiation

1 reference

12 December 2020

Various parameters for grading acne vulgaris

1 reference

12 December 2020

Benoxaprofen for nodular acne

1 reference

12 December 2020

Is acne vulgaris a genuine inflammatory disease?

1 reference

12 December 2020

Identifiers

DOI

10.4161/DERM.1.3.8368

1 reference

28 July 2017

1 reference

28 July 2017

1 reference

PubMed ID

20436887