Laureate ESCI award for excellence in clinical science 1999. Cytokines and the human immunodeficiency virus: from bench to bedside. European Society for Clinical Investigation (Q33717470)

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English	Laureate ESCI award for excellence in clinical science 1999. Cytokines and the human immunodeficiency virus: from bench to bedside. European Society for Clinical Investigation	scientific article

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scholarly article

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Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

Laureate ESCI award for excellence in clinical science 1999. Cytokines and the human immunodeficiency virus: from bench to bedside. European Society for Clinical Investigation (English)

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Europe PubMed Central

28 July 2017

author name string

Poli G

1

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Europe PubMed Central

28 July 2017

publication date

1 August 1999

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Europe PubMed Central

28 July 2017

European Journal of Clinical Investigation

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Europe PubMed Central

28 July 2017

29

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Europe PubMed Central

28 July 2017

8

1 reference

Europe PubMed Central

28 July 2017

723-732

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Europe PubMed Central

28 July 2017

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

1 reference

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Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

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21 January 2018

Recovery of replication-competent HIV despite prolonged suppression of plasma viremia

1 reference

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21 January 2018

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

1 reference

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21 January 2018

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

1 reference

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21 January 2018

NIH conference. Immunopathogenic mechanisms in human immunodeficiency virus (HIV) infection

1 reference

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21 January 2018

Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study

1 reference

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21 January 2018

Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus

1 reference

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21 January 2018

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1 reference

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Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS)

1 reference

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21 January 2018

The origin and evolution of human T-cell lymphotropic virus types I and II.

1 reference

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21 January 2018

HTLV-1-associated diseases

1 reference

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Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirus

1 reference

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Biological and biochemical characterization of a cloned Leu-3- cell surviving infection with the acquired immune deficiency syndrome retrovirus

1 reference

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21 January 2018

Induction of HTLV-III/LAV from a nonvirus-producing T-cell line: implications for latency

1 reference

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21 January 2018

Long-term cultures of HTLV-III--infected T cells: a model of cytopathology of T-cell depletion in AIDS.

1 reference

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21 January 2018

Negative regulation of human immune deficiency virus replication in monocytes. Distinctions between restricted and latent expression in THP-1 cells

1 reference

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21 January 2018

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1 reference

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21 January 2018

Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation

1 reference

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21 January 2018

Human immunodeficiency virus (HIV) infection in CD4+ T lymphocytes genetically deficient in LFA-1: LFA-1 is required for HIV-mediated cell fusion but not for viral transmission

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat

1 reference

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21 January 2018

A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-kappa B subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells

1 reference

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21 January 2018

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor alpha and interleukin 6 induction of virus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

HIV replication in CD4+ T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous beta-chemokines and the viral inductive effects of other endogenous cytokines

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages

1 reference

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21 January 2018

CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Human CD8+ cell non-cytolytic anti-HIV activity mediated by a novel cytokine

1 reference

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21 January 2018

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

HIV suppression by interleukin-16.

1 reference

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21 January 2018

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

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21 January 2018

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.

1 reference

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21 January 2018

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

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The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1 reference

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Monocyte chemotactic protein-2 activates CCR5 and blocks CD4/CCR5-mediated HIV-1 entry/replication

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

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How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity

1 reference

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Chemokine receptors: keys to AIDS pathogenesis?

1 reference

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The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

1 reference

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Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1 reference

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Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

1 reference

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Genetic polymorphism of CCR5 gene and HIV disease: the heterozygous (CCR5/delta ccr5) genotype is neither essential nor sufficient for protection against disease progression. Swiss HIV Cohort.

1 reference

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Inhibition of HIV-1 infection by the beta-chemokine MDC

1 reference

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21 January 2018

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1 reference

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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1 reference

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The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.

1 reference

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Increased replication of T-cell-tropic HIV strains and CXC-chemokine receptor-4 induction in T cells treated with macrophage inflammatory protein (MIP)-1alpha, MIP-1beta and RANTES beta-chemokines

1 reference

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21 January 2018

CC-chemokines enhance the replication of T-tropic strains of HIV-1 in CD4(+) T cells: role of signal transduction

1 reference

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A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

1 reference

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21 January 2018

Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression

1 reference

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21 January 2018

The amino-terminal domain of the CCR2 chemokine receptor acts as coreceptor for HIV-1 infection

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Plasma levels of monocyte chemoattractant protein-1 but not those of macrophage inhibitory protein-1alpha and RANTES correlate with virus load in human immunodeficiency virus infection

1 reference

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Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

1 reference

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21 January 2018

Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Direct polyclonal activation of human B lymphocytes by the acquired immune deficiency syndrome virus

1 reference

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Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes

1 reference

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21 January 2018

Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection

1 reference

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21 January 2018

Transforming growth factor-beta and suppression of humoral immune responses in HIV infection

1 reference

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21 January 2018

Macrophage- and astrocyte-derived transforming growth factor beta as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome

1 reference

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21 January 2018

Jaks and STATs: biological implications

1 reference

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Positive selection of apoptosis-resistant cells correlates with activation of dominant-negative STAT5.

1 reference

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Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Efficacy of low doses of the polyethylene glycol derivative of interleukin-2 in modulating the immune response of patients with human immunodeficiency virus type 1 infection

1 reference

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21 January 2018

Rational interleukin 2 therapy for HIV positive individuals: daily low doses enhance immune function without toxicity

1 reference

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21 January 2018

Subcutaneous administration of interleukin-2 in human immunodeficiency virus type 1-infected persons

1 reference

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21 January 2018

Effects of subcutaneous interleukin-2 therapy on CD4 subsets and in vitro cytokine production in HIV+ subjects

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Effects of TH1 and TH2 cytokines on CD8+ cell response against human immunodeficiency virus: implications for long-term survival

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Cytokines alter production of HIV-1 from primary mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Induction of HIV-1 replication by type 1-like cytokines, interleukin (IL)-12 and IL-15: effect on viral transcriptional activation, cellular proliferation, and endogenous cytokine production

1 reference

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21 January 2018

Interleukin 18 stimulates HIV type 1 in monocytic cells

1 reference

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21 January 2018

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interferon-alpha but not AZT suppresses HIV expression in chronically infected cell lines

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Recombinant interleukin 4 stimulates human immunodeficiency virus production by infected monocytes and macrophages

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interleukin-12 decreases human immunodeficiency virus type 1 replication in human macrophage cultures reconstituted with autologous peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Transforming growth factor beta suppresses human immunodeficiency virus expression and replication in infected cells of the monocyte/macrophage lineage

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Retinoic acid mimics transforming growth factor beta in the regulation of human immunodeficiency virus expression in monocytic cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Interferon gamma induces the expression of human immunodeficiency virus in persistently infected promonocytic cells (U1) and redirects the production of virions to intracytoplasmic vacuoles in phorbol myristate acetate-differentiated U1 cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

CCR2 Polymorphism and HIV Disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2362.1999.00525.X

21 January 2018

Identifiers

10.1046/J.1365-2362.1999.00525.X

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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