Identification of the minimal functional unit of the homo-oligomeric human reduced folate carrier (Q33717581)

28 July 2017

title

Identification of the minimal functional unit of the homo-oligomeric human reduced folate carrier (English)

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28 July 2017

1 reference

Zhanjun Hou

1

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28 July 2017

Christina Cherian

2

1 reference

28 July 2017

Joseph Drews

3

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28 July 2017

Jianmei Wu

4

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28 July 2017

Larry H Matherly

5

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28 July 2017

language of work or name

English

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publication date

17 December 2009

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Journal of Biological Chemistry

28 July 2017

published in

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28 July 2017

volume

285

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28 July 2017

issue

7

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28 July 2017

page(s)

4732-4740

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Oligomeric structure of the human reduced folate carrier: identification of homo-oligomers and dominant-negative effects on carrier expression and function

28 July 2017

cites work

1 reference

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Structure and function of the reduced folate carrier a paradigm of a major facilitator superfamily mammalian nutrient transporter

21 June 2018

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21 June 2018

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Structure-based functional study reveals multiple roles of transmembrane segment IX and loop VIII-IX in NhaA Na+/H+ antiporter of Escherichia coli at physiological pH

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21 June 2018

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Human reduced folate carrier: translation of basic biology to cancer etiology and therapy

21 June 2018

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Effects of 5' untranslated region diversity on the posttranscriptional regulation of the human reduced folate carrier

21 June 2018

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Transmembrane domains 4, 5, 7, 8, and 10 of the human reduced folate carrier are important structural or functional components of the transmembrane channel for folate substrates

21 June 2018

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21 June 2018

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Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome

21 June 2018

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Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods

21 June 2018

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Functional interactions between the subunits of the lactose transporter from Streptococcus thermophilus

21 June 2018

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Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier.

21 June 2018

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21 June 2018

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21 June 2018

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Resistance to antifolates

21 June 2018

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Membrane transport of folates

21 June 2018

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Characterization of a cysteine-less human reduced folate carrier: localization of a substrate-binding domain by cysteine-scanning mutagenesis and cysteine accessibility methods

21 June 2018

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Quaternary structure and function of transport proteins

21 June 2018

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The lactose transport protein is a cooperative dimer with two sugar translocation pathways

21 June 2018

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21 June 2018

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Carrier-mediated membrane transport of folates in mammalian cells

21 June 2018

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Dominant negative isoform of rat norepinephrine transporter produced by alternative RNA splicing

21 June 2018

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Negative dominance studies demonstrate the oligomeric structure of EmrE, a multidrug antiporter from Escherichia coli.

21 June 2018

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Intramolecular fusion of Na pump subunits assures exclusive assembly of the fused alpha and beta subunit domains into a functional enzyme in cells also expressing endogenous Na pump subunits.

21 June 2018

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Properties of permease dimer, a fusion protein containing two lactose permease molecules from Escherichia coli

21 June 2018

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Prolonged association of temperature-sensitive mutants of human P-glycoprotein with calnexin during biogenesis.

21 June 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 June 2018

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Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes

21 June 2018

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Determination of the subunit stoichiometry of a voltage-activated potassium channel

21 June 2018

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Monomers of the NhaA Na+/H+ antiporter of Escherichia coli are fully functional yet dimers are beneficial under extreme stress conditions at alkaline pH in the presence of Na+ or Li+.

21 June 2018

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Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

21 January 2018

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Hourglass pore-forming domains restrict aquaporin-1 tetramer assembly.

21 January 2018

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Monomeric and dimeric byproducts are the principal functional elements of higher order P2X1 concatamers

21 January 2018

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Oligomeric structure of the neutral amino acid transporters KAAT1 and CAATCH1.

21 January 2018

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Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells

21 January 2018

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12 December 2020

A model system for the study of heteroexchange diffusion: Methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells

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12 December 2020

The characteristics of the membrane transport of amethopterin and the naturally occurring folates

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12 December 2020

Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro

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12 December 2020

Identifiers

DOI

10.1074/JBC.M109.086033

1 reference

28 July 2017

1 reference

28 July 2017

1 reference