Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway (Q33719089)

28 July 2017

title

Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway (English)

1 reference

28 July 2017

0 references

Teresa Jover-Mengual

1

1 reference

28 July 2017

Takahiro Miyawaki

2

1 reference

28 July 2017

Adrianna Latuszek

3

1 reference

28 July 2017

Enrique Alborch

4

1 reference

28 July 2017

R Suzanne Zukin

5

1 reference

28 July 2017

Anne M Etgen

6

1 reference

28 July 2017

language of work or name

English

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publication date

28 January 2010

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28 July 2017

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28 July 2017

volume

1321

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28 July 2017

page(s)

1-12

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Estradiol rescues neurons from global ischemia-induced cell death: multiple cellular pathways of neuroprotection

28 July 2017

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Pretreatment with a single estradiol-17beta bolus activates cyclic-AMP response element binding protein and protects CA1 neurons against global cerebral ischemia

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Rapid enhancement of two-step wiring plasticity by estrogen and NMDA receptor activity

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Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons

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Acute pretreatment with estradiol protects against CA1 cell loss and spatial learning impairments resulting from transient global ischemia

21 June 2018

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MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia

21 June 2018

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Acute and chronic estradiol treatments reduce memory deficits induced by transient global ischemia in female rats

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Ischemic insults derepress the gene silencer REST in neurons destined to die

21 June 2018

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21 June 2018

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21 June 2018

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Programmed cell death in cerebral ischemia

21 June 2018

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Neuroprotection by estradiol.

21 June 2018

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Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Estrogen: mechanisms for a rapid action in CA1 hippocampal neurons

21 June 2018

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21 June 2018

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21 June 2018

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Estrogen facilitates induction of long term potentiation in the hippocampus of awake rats

21 June 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 June 2018

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21 June 2018

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Differential regulation of NMDAR1 mRNA and protein by estradiol in the rat hippocampus.

21 June 2018

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21 June 2018

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Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism

21 June 2018

1 reference

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Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat.

21 June 2018

1 reference

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The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death

21 June 2018

1 reference

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17beta-estradiol and enriched environment accelerate cognitive recovery after focal brain ischemia.

30 October 2018

1 reference

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alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionate attenuates glutamate-induced caspase-3 cleavage via regulation of glycogen synthase kinase 3beta

30 October 2018

1 reference

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beta-Estradiol induces synaptogenesis in the hippocampus by enhancing brain-derived neurotrophic factor release from dentate gyrus granule cells

30 October 2018

1 reference

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17beta-estradiol pretreatment prevents the global ischemic injury-induced decrease of Akt activation and bad phosphorylation in gerbils

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estradiol-induced increase in the magnitude of long-term potentiation is prevented by blocking NR2B-containing receptors.

30 October 2018

1 reference

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Chronic 17beta-estradiol pretreatment and ischemia-induced hippocampal degeneration and memory impairments: a 6-month survival study.

30 October 2018

1 reference

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Activation of the Akt/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estradiol prevents the focal cerebral ischemic injury-induced decrease of forkhead transcription factors phosphorylation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estrogen-induced increase in the magnitude of long-term potentiation occurs only when the ratio of NMDA transmission to AMPA transmission is increased.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estradiol protects against oxygen and glucose deprivation in rat hippocampal organotypic cultures and activates Akt and inactivates GSK-3beta.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estrogen can act via estrogen receptor alpha and beta to protect hippocampal neurons against global ischemia-induced cell death.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Ischemic preconditioning: neuronal survival in the face of caspase-3 activation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Copper-Zinc Superoxide Dismutase Affects Akt Activation After Transient Focal Cerebral Ischemia in Mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Decreased akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

DMSO as a vehicle for central injections: tests with feeding elicited by norepinephrine injected into the paraventricular nucleus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Detection of caspase activation in situ by fluorochrome-labeled caspase inhibitors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Estrogen modulates sexually dimorphic contextual fear conditioning and hippocampal long-term potentiation (LTP) in rats(1).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Novel mechanism for non-genomic action of 17 beta-oestradiol on kainate-induced currents in isolated rat CA1 hippocampal neurones

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836484

Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood

30 October 2018

1 reference

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Ovarian steroids and selective estrogen receptor modulators activity on rat brain NMDA and AMPA receptors

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20114038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20114038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Serine-threonine protein kinase Akt does not mediate ischemic tolerance after global ischemia in the gerbil

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20114038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BRAINRES.2010.01.046

1 reference

28 July 2017

1 reference

28 July 2017

1 reference