Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes (Q33720458)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1326671%20AND%20SRC:MED&resulttype=core&format=json

18 September 2019

title

Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes (English)

1 reference

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18 September 2019

1 reference

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13 September 2022

human papilloma virus

1 reference

human papillomavirus

29 September 2024

N. L. Hubbert

1

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13 September 2022

S. A. Sedman

series ordinal

2

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13 September 2022

J. T. Schiller

series ordinal

3

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13 September 2022

language of work or name

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1 October 1992

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full work available at URL

18 September 2019

http://jvi.asm.org/cgi/content/abstract/66/10/6237

online access status

open access

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1326671/pdf/?tool=EBI

13 September 2022

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1326671

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1326671/?tool=EBI

13 September 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1326671

https://europepmc.org/articles/PMC283680

13 September 2022

1 reference

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https://europepmc.org/articles/PMC283680?pdf=render

13 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1326671

13 September 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1326671%20AND%20SRC:MED&resulttype=core&format=json

18 September 2019

volume

66

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18 September 2019

issue

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1326671%20AND%20SRC:MED&resulttype=core&format=json

18 September 2019

page(s)

6237-6241

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Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed Cells

18 September 2019

cites work

1 reference

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Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.

21 June 2018

1 reference

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Molecular basis for heterogeneity of the human p53 protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283680

Different human cervical carcinoma cell lines show similar transcription patterns of human papillomavirus type 18 early genes

21 June 2018

1 reference

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Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein

21 June 2018

1 reference

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Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

21 June 2018

1 reference

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Rearrangement of the p53 gene in human osteogenic sarcomas

21 June 2018

1 reference

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Chromosomal integration sites of human papillomavirus DNA in three cervical cancer cell lines mapped by in situ hybridization

21 June 2018

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HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes

21 June 2018

1 reference

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Mutations in the p53 gene occur in diverse human tumour types

21 June 2018

1 reference

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Wild-type p53 can inhibit oncogene-mediated focus formation

21 June 2018

1 reference

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The p53 proto-oncogene can act as a suppressor of transformation

21 June 2018

1 reference

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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283680

Characterization of normal human exocervical epithelial cells immortalized in vitro by papillomavirus types 16 and 18 DNA.

21 June 2018

1 reference

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Epidermal differentiation: the bare essentials

21 June 2018

1 reference

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283680

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283680

Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283680

Suppression of human colorectal carcinoma cell growth by wild-type p53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283680

In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential

21 June 2018

1 reference

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Stability of p53 protein in rat cells transformed by various viral transforming genes

21 June 2018

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A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18

21 June 2018

1 reference

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Loss of p53 protein in human papillomavirus type 16 E6-immortalized human mammary epithelial cells

21 June 2018

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Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

21 June 2018

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The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283680

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines

21 June 2018

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p53 point mutation in HPV negative human cervical carcinoma cell lines

21 June 2018

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Mutant p53 can substitute for human papillomavirus type 16 E6 in immortalization of human keratinocytes but does not have E6-associated trans-activation or transforming activity

21 June 2018

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Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies

21 June 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/1326671