Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks (Q33725093)

28 July 2017

Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks (English)

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28 July 2017

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Charles R Farber

19

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Marc L. Reitman

object named as

Marc L Reitman

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Aldons Jake Lusis

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object named as

Aldons J Lusis

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Margarete Mehrabian

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Eric E Schadt

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Atila van Nas

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Anatole Ghazalpour

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28 July 2017

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Susanna S Wang

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Joshua L Deignan

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28 July 2017

Lawrence W Castellani

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object named as

Lawrence W Castellani

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Pek Y Lum

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28 July 2017

Xia Yang

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28 July 2017

Hongxiu Qi

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28 July 2017

Jun Zhu

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28 July 2017

Su Qian

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28 July 2017

Judy Zhong

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28 July 2017

Gevork Torosyan

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28 July 2017

Sana Majid

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Brie Falkard

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Robert R Kleinhanz

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Jenny Karlsson

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Sheena Mumick

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Kai Wang

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Tao Xie

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Michael Coon

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28 July 2017

Chunsheng Zhang

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Daria Estrada-Smith

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Bin Zhang

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Douglas J Macneil

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John R Lamb

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Katrina M Dipple

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Thomas A Drake

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language of work or name

English

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publication date

8 March 2009

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28 July 2017

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41

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28 July 2017

415-423

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28 July 2017

4

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https://scigraph.springernature.com/pub.10.1038/ng.325

28 July 2017

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Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

21 June 2018

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Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress

21 June 2018

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Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

21 June 2018

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Mapping the genetic architecture of gene expression in human liver

21 June 2018

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Common variants near MC4R are associated with fat mass, weight and risk of obesity

21 June 2018

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Common genetic variation near MC4R is associated with waist circumference and insulin resistance

21 June 2018

1 reference

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Variations in DNA elucidate molecular networks that cause disease

21 June 2018

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Genetics of gene expression and its effect on disease

21 June 2018

1 reference

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease

21 June 2018

1 reference

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Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

21 June 2018

1 reference

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Moving toward a system genetics view of disease

21 June 2018

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Network-based analysis of affected biological processes in type 2 diabetes models

21 June 2018

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 June 2018

1 reference

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 June 2018

1 reference

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Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations

21 June 2018

1 reference

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Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling

21 June 2018

1 reference

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Unraveling the genetics of human obesity

21 June 2018

1 reference

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Tissue-specific expression and regulation of sexually dimorphic genes in mice

21 June 2018

1 reference

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Malic enzyme 1 genotype is associated with backfat thickness and meat quality traits in pigs.

21 June 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 June 2018

1 reference

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Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase

21 June 2018

1 reference

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Genomic analysis of metabolic pathway gene expression in mice

21 June 2018

1 reference

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An integrative genomics approach to infer causal associations between gene expression and disease

21 June 2018

1 reference

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Cis-acting expression quantitative trait loci in mice

21 June 2018

1 reference

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The PANTHER database of protein families, subfamilies, functions and pathways

21 June 2018

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Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.

21 June 2018

1 reference

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Genetic inheritance of gene expression in human cell lines

21 June 2018

1 reference

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Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase

21 June 2018

1 reference

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Statistical significance for genomewide studies

21 June 2018

1 reference

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Microarray standard data set and figures of merit for comparing data processing methods and experiment designs

21 June 2018

1 reference

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Genetics of gene expression surveyed in maize, mouse and man

21 June 2018

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The hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP

21 June 2018

1 reference

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Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

21 June 2018

1 reference

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A transgenic model of visceral obesity and the metabolic syndrome

21 June 2018

1 reference

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Gene ontology: tool for the unification of biology

21 June 2018

1 reference

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gas7: A gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837947

X-linked glycerol kinase deficiency in the mouse leads to growth retardation, altered fat metabolism, autonomous glucocorticoid secretion and neonatal death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837947

Thermosensitive phenotype of transgenic mice overproducing human glutathione peroxidases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837947

A common genetic variant is associated with adult and childhood obesity

21 June 2018

1 reference

Chemokine expression in transgenic mice overproducing human glutathione peroxidases

21 January 2018

1 reference

Adipose gene expression response of lean and obese mice to short-term dietary restriction.

21 January 2018

1 reference

Deficiency in cytosolic malic enzyme does not increase acetaminophen-induced hepato-toxicity

21 January 2018

1 reference

Functional annotation of a full-length mouse cDNA collection

21 January 2018

1 reference

Rosetta error model for gene expression analysis.

21 January 2018

1 reference

Complement C3a receptors in the pituitary gland: a novel pathway by which an innate immune molecule releases hormones involved in the control of inflammation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837947

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19270708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19270708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of the Gas7 gene and Oct4 in embryonic stem cells of mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19270708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.325

1 reference

28 July 2017

1 reference

28 July 2017

1 reference