Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection. (Q33725192)

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English	Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection.	scientific article

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17 January 2020

Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection (English)

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17 January 2020

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Maria Leonor S. Oliveira

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Michelle Darrieux

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Eliane N Miyaji

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Daniela M Ferreira

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Daniela M Ferreira

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Adriana T Moreno

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Paulo L Ho

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Jorge M C Ferreira

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Fabiana C Pimenta

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Ana Lúcia S S Andrade

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20 January 2010

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Clinical and Vaccine Immunology

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3

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439-446

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17 January 2020

PspA family fusion proteins delivered by attenuated Salmonella enterica serovar Typhimurium extend and enhance protection against Streptococcus pneumoniae

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21 June 2018

PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation

1 reference

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21 June 2018

Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998-2004.

1 reference

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21 June 2018

Streptococcus pneumoniae protein vaccine candidates: properties, activities and animal studies

1 reference

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21 June 2018

Effect of the seven-valent conjugate pneumococcal vaccine on carriage and drug resistance of Streptococcus pneumoniae in healthy children attending day-care centers in Lisbon

1 reference

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21 June 2018

PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin [corrected].

1 reference

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21 June 2018

Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface

1 reference

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21 June 2018

Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model

1 reference

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21 June 2018

Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837969

21 June 2018

Novel surface attachment mechanism of the Streptococcus pneumoniae protein PspA

1 reference

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21 June 2018

Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis

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21 June 2018

Vaccine-induced human antibodies to PspA augment complement C3 deposition on Streptococcus pneumoniae.

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30 October 2018

Post-PCV7 changes in colonizing pneumococcal serotypes in 16 Massachusetts communities, 2001 and 2004.

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30 October 2018

PspA family typing and PCR-based DNA fingerprinting with BOX A1R primer of pneumococci from the blood of patients in the USA with and without sickle cell disease.

1 reference

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30 October 2018

A high-copy T7 Escherichia coli expression vector for the production of recombinant proteins with a minimal N-terminal His-tagged fusion peptide.

1 reference

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30 October 2018

Protective efficacy of PspA (pneumococcal surface protein A)-based DNA vaccines: contribution of both humoral and cellular immune responses.

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30 October 2018

Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089795

12 December 2020

based on heuristic

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Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089795

12 December 2020

based on heuristic

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Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of pneumococcal isolates by antisera raised against PspA fragments from different clades

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089795

12 December 2020

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10.1128/CVI.00430-09

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17 January 2020

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24 November 2022

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17 January 2020

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