Molecular characterization, expression, and in vivo analysis of LmexCht1: the chitinase of the human pathogen, Leishmania mexicana. (Q33732054)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15561707%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

title

Molecular characterization, expression, and in vivo analysis of LmexCht1: the chitinase of the human pathogen, Leishmania mexicana (English)

1 reference

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30 August 2019

Leishmania mexicana

1 reference

6

1 reference

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30 August 2019

author name string

Manju B Joshi

1

1 reference

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30 August 2019

Matthew E Rogers

2

1 reference

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30 August 2019

Alison M Shakarian

3

1 reference

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30 August 2019

Mat Yamage

4

1 reference

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30 August 2019

Saeed A Al-Harthi

5

1 reference

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30 August 2019

Dennis M Dwyer

7

1 reference

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30 August 2019

language of work or name

English

0 references

publication date

22 November 2004

1 reference

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Journal of Biological Chemistry

30 August 2019

published in

1 reference

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30 August 2019

volume

280

1 reference

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30 August 2019

issue

5

1 reference

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30 August 2019

page(s)

3847-3861

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Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation

30 August 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Plasma chitotriosidase activity in acute Plasmodium falciparum malaria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Endogenous interleukin-12 is critical for controlling the late but not the early stage of Leishmania mexicana infection in C57BL/6 mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Molecular dissection of the functional domains of a unique, tartrate-resistant, surface membrane acid phosphatase in the primitive human pathogen Leishmania donovani

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Developmentally regulated expression of a cell surface class I nuclease in Leishmania mexicana

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Molecular aspects of parasite-vector and vector-host interactions in leishmaniasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

A unique surface membrane anchored purine-salvage enzyme is conserved among a group of primitive eukaryotic human pathogens.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Leishmaniasis: current status of vaccine development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Identification of a novel acidic mammalian chitinase distinct from chitotriosidase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Genomic organization, transcription, splicing and gene regulation in Leishmania

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Strong induction of members of the chitinase family of proteins in atherosclerosis: chitotriosidase and human cartilage gp-39 expressed in lesion macrophages.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Inducible expression of suicide genes in Leishmania donovani amastigotes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

The Ld Cht1 gene encodes the secretory chitinase of the human pathogen Leishmania donovani

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

A novel role for the peritrophic matrix in protecting Leishmania from the hydrolytic activities of the sand fly midgut.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the golgi apparatus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3'-untranslated region

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Multiple domain structure in a chitinase gene (chiC) of Streptomyces lividans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Leishmaniases of the New World: current concepts and implications for future research

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Sequence of a cDNA and expression of the gene encoding epidermal and gut chitinases of Manduca sexta

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Complete developmental cycle of Leishmania mexicana in axenic culture.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Identification of glutamic acid 204 and aspartic acid 200 in chitinase A1 of Bacillus circulans WL-12 as essential residues for chitinase activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Crystal structure of endo-beta-N-acetylglucosaminidase F1, an alpha/beta-barrel enzyme adapted for a complex substrate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Molecular characterization of a novel tobacco pathogenesis-related (PR) protein: a new plant chitinase/lysozyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Crystal structures of hevamine, a plant defence protein with chitinase and lysozyme activity, and its complex with an inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Crystal structure of a bacterial chitinase at 2.3 A resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Crystal structure of endo-beta-N-acetylglucosaminidase H at 1.9 A resolution: active-site geometry and substrate recognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Developmental gene expression in Leishmania donovani: differential cloning and analysis of an amastigote-stage-specific gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

A simple method for displaying the hydropathic character of a protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

A comprehensive set of sequence analysis programs for the VAX

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

21 June 2018

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Signal sequences. The limits of variation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Beta tubulin gene of the parasitic protozoan Leishmania mexicana

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Discontinuous transcription and antigenic variation in trypanosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Nucleotide sequence of the chitinase B gene of Serratia marcescens QMB1466.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Leishmania donovani: immunochemical localization and secretory mechanism of soluble acid phosphatase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Gene cloning of chitinase A1 from Bacillus circulans WL-12 revealed its evolutionary relationship to Serratia chitinase and to the type III homology units of fibronectin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Trans splicing of nuclear pre-mRNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

A classification of glycosyl hydrolases based on amino acid sequence similarities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Rapid and reliable fluorescent cycle sequencing of double-stranded templates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Transmission-blocking antibodies recognize microfilarial chitinase in brugian lymphatic filariasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Cloning and expression of the cDNA sequence encoding the lysosomal glycosidase di-N-acetylchitobiase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

What's new in chitinase research?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Axenic cultivation and characterization of Leishmania mexicana amastigote-like forms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Purification of two chitinases from Rhizopus oligosporus and isolation and sequencing of the encoding genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Leishmania infections damage the feeding mechanism of the sandfly vector and implement parasite transmission by bite

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Chitinase secreted by Leishmania functions in the sandfly vector.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Leishmania mexicana: induction of metacyclogenesis by cultivation of promastigotes at acidic pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Members of a unique histidine acid phosphatase family are conserved amongst a group of primitive eukaryotic human pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Genetic nomenclature for Trypanosoma and Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Mini-exon gene variation in human pathogenic Leishmania species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Identification and overexpression of the A2 amastigote-specific protein in Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Molecular cloning and ethylene-inducible expression of Chib1 chitinase from soybean (Glycine max (L.) Merr.).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Elevated plasma chitotriosidase activity in various lysosomal storage disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412299200

Leishmania mexicana cysteine proteinase-deficient mutants have attenuated virulence for mice and potentiate a Th1 response.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Splicing and 3'-processing of the tyrosine tRNA of Trypanosoma brucei.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Phosphatidylinositol glycan (PI-G) anchored membrane proteins. Amino acid requirements adjacent to the site of cleavage and PI-G attachment in the COOH-terminal signal peptide.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839926

Hevamine, a chitinase from the rubber tree Hevea brasiliensis, cleaves peptidoglycan between the C-1 of N-acetylglucosamine and C-4 of N-acetylmuramic acid and therefore is not a lysozyme

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15561707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dissection of the functional domains of the Leishmania surface membrane 3'-nucleotidase/nuclease, a unique member of the class I nuclease family

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15561707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pathogenic leishmania secrete antigenically related chitinases which are encoded by a highly conserved gene locus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15561707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M412299200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15561707%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15561707%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference