Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease (Q33732191)

29 July 2017

title

Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease (English)

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29 July 2017

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Jean-Cosme Dodart

1

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29 July 2017

Robert A Marr

2

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29 July 2017

Milla Koistinaho

3

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29 July 2017

Beth M Gregersen

4

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29 July 2017

Seema Malkani

5

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29 July 2017

Inder M Verma

6

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29 July 2017

Steven M Paul

7

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29 July 2017

language of work or name

English

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publication date

18 January 2005

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29 July 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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29 July 2017

volume

102

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29 July 2017

issue

4

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29 July 2017

page(s)

1211-1216

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Pathways towards and away from Alzheimer's disease

29 July 2017

cites work

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

21 June 2018

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Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

21 January 2018

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Neuroanatomical abnormalities in behaviorally characterized APP(V717F) transgenic mice.

21 January 2018

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Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype

21 January 2018

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

21 January 2018

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Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging

21 January 2018

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Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly.

30 October 2018

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Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.

30 October 2018

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Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

30 October 2018

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12 December 2020

Apolipoprotein E4 promotes the early deposition of Abeta42 and then Abeta40 in the elderly

1 reference

12 December 2020

Apolipoprotein E and Alzheimer's disease

1 reference

12 December 2020

Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures

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12 December 2020

Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0409072102

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29 July 2017

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29 July 2017

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