Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation (Q33732463)

29 July 2017

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation (English)

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29 July 2017

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Marileila Varella-Garcia

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object named as

Marileila Varella-Garcia

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29 July 2017

Wei Guo

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29 July 2017

Joseph L Lasky

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29 July 2017

Chun-Ju Chang

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29 July 2017

Sherly Mosessian

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Xiaoman Lewis

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29 July 2017

Yun Xiao

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Jennifer E Yeh

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James Y Chen

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29 July 2017

M Luisa Iruela-Arispe

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29 July 2017

Hong Wu

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29 July 2017

language of work or name

English

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publication date

7 May 2008

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29 July 2017

453

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7194

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529-533

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https://scigraph.springernature.com/pub.10.1038/nature06933

29 July 2017

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cites work

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Essential role for nuclear PTEN in maintaining chromosomal integrity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Stem cell research: paths to cancer therapies and regenerative medicine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

A role for Wnt signalling in self-renewal of haematopoietic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Stem cells, cancer, and cancer stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Translocations involving c-myc and c-myc function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Expression of myeloid markers lacks prognostic impact in children treated for acute lymphoblastic leukemia: Italian experience in AIEOP-ALL 88-91 studies.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840044

Detection of E2A translocations in leukemias via fluorescence in situ hybridization

30 October 2018

1 reference

12 December 2020

Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias

1 reference

12 December 2020

Immunophenotyping of acute leukemia by flow cytometric analysis. Use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis

1 reference

12 December 2020

Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia

1 reference

12 December 2020

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

12 December 2020

Tumor growth need not be driven by rare cancer stem cells

2 references

12 December 2020

Crossref

https://api.crossref.org/works/10.1038%2FNATURE06933

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE06933

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Dimensions Publication ID

29 July 2017

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29 July 2017

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