Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression (Q33734803)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

main subject

human papilloma virus

1 reference

human papillomavirus

29 September 2024

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Peter Howley

7

1 reference

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17 January 2020

5

Matthias Ottinger

1 reference

17 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

Jennifer A Smith

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Elizabeth A White

2

1 reference

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17 January 2020

Mathew E Sowa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Maria L C Powell

4

1 reference

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17 January 2020

language of work or name

English

0 references

publication date

2 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

107

1 reference

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17 January 2020

issue

8

1 reference

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17 January 2020

page(s)

3752-3757

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression

17 January 2020

cites work

1 reference

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Cell-type specific transcriptional activities among different papillomavirus long control regions and their regulation by E2.

21 June 2018

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Identification of genes that regulate epithelial cell migration using an siRNA screening approach

21 June 2018

1 reference

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Papillomaviruses in the causation of human cancers - a brief historical account

21 June 2018

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Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc

21 June 2018

1 reference

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Identification of host proteins required for HIV infection through a functional genomic screen

21 June 2018

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Repression of Smad3 activity by histone demethylase SMCX/JARID1C

21 June 2018

1 reference

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Brd4-independent transcriptional repression function of the papillomavirus e2 proteins

21 June 2018

1 reference

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p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing

21 June 2018

1 reference

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The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.

21 June 2018

1 reference

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The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

21 June 2018

1 reference

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Structure of the papillomavirus DNA-tethering complex E2:Brd4 and a peptide that ablates HPV chromosomal association

21 June 2018

1 reference

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Brd4 links chromatin targeting to HPV transcriptional silencing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840515

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

21 June 2018

1 reference

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Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression

21 June 2018

1 reference

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Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

21 June 2018

1 reference

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Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans

21 June 2018

1 reference

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The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840515

Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840515

The p400 complex is an essential E1A transformation target

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840515

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

21 June 2018

1 reference

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Mechanisms of human papillomavirus E2-mediated repression of viral oncogene expression and cervical cancer cell growth inhibition

21 June 2018

1 reference

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Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells.

21 June 2018

1 reference

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Tip60 acetylates six lysines of a specific class in core histones in vitro

21 June 2018

1 reference

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The chromatin structure of the long control region of human papillomavirus type 16 represses viral oncoprotein expression.

21 June 2018

1 reference

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Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines

21 June 2018

1 reference

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Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis

21 June 2018

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p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen

21 June 2018

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Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene

21 June 2018

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Human papillomavirus type 11 E2 proteins repress the homologous E6 promoter by interfering with the binding of host transcription factors to adjacent elements.

21 June 2018

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Suppression of cellular proliferation by the papillomavirus E2 protein

21 June 2018

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Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

21 June 2018

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Different human cervical carcinoma cell lines show similar transcription patterns of human papillomavirus type 18 early genes

21 June 2018

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Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines

21 June 2018

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Structure and transcription of human papillomavirus sequences in cervical carcinoma cells

21 June 2018

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Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains.

21 June 2018

1 reference

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The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region

21 June 2018

1 reference

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The human papillomavirus type 18 (HPV18) E2 gene product is a repressor of the HPV18 regulatory region in human keratinocytes.

21 June 2018

1 reference

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The papillomavirus E2 regulatory proteins.

21 June 2018

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The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840515

Functional analysis of E2-mediated repression of the HPV18 P105 promoter

21 June 2018

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Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins including the retinoblastoma protein and cyclin A

21 June 2018

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Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0914818107

Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0914818107

The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0914818107

The physical state of human papillomavirus type 16 DNA in benign and malignant genital tumours

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20133580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0914818107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

20133580

1 reference