Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils (Q33743772)

29 July 2017

title

Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils (English)

1 reference

29 July 2017

1 reference

Monica Bucciantini

5

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Alessandra Corazza

Alessandra Corazza

6

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Massimo Stefani

Massimo Stefani

15

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Federico Fogolari

Federico Fogolari

7

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Mario Salmona

Mario Salmona

9

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Sara Raimondi

2

Sara Raimondi

1 reference

29 July 2017

13

Riccardo Porcari

1 reference

29 July 2017

1

Sofia Giorgetti

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29 July 2017

18

Monica Stoppini

1 reference

29 July 2017

4

Annalisa Relini

1 reference

29 July 2017

3

Katiuscia Pagano

1 reference

29 July 2017

8

Luca Codutti

1 reference

29 July 2017

10

Palma Mangione

1 reference

29 July 2017

17

Vittorio Bellotti

1 reference

29 July 2017

Lino Colombo

11

1 reference

29 July 2017

Ada De Luigi

12

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29 July 2017

Alessandra Gliozzi

14

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29 July 2017

Gennaro Esposito

16

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29 July 2017

language of work or name

English

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publication date

10 November 2010

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Journal of Biological Chemistry

29 July 2017

published in

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29 July 2017

volume

286

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29 July 2017

issue

3

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29 July 2017

page(s)

2121-2131

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A causative link between the structure of aberrant protein oligomers and their toxicity.

29 July 2017

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1 reference

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NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1

28 July 2018

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beta2-Microglobulin is potentially neurotoxic, but the blood brain barrier is likely to protect the brain from its toxicity

28 July 2018

1 reference

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The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties

28 July 2018

1 reference

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Beta2-microglobulin stimulates osteoclast formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

The efficacy of tetracyclines in peripheral and intracerebral prion infection.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

The workings of the amyloid diseases

28 July 2018

1 reference

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Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis.

28 July 2018

1 reference

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Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Curli biogenesis and function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Tetracycline inhibits W7FW14F apomyoglobin fibril extension and keeps the amyloid protein in a pre-fibrillar, highly cytotoxic state

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease".

28 July 2018

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A randomized, controlled trial of doxycycline and rifampin for patients with Alzheimer's disease

28 July 2018

1 reference

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Doxycycline and other tetracyclines in the treatment of bone metastasis

28 July 2018

1 reference

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Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid.

28 July 2018

1 reference

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Beta2-microglobulin induces caspase-dependent apoptosis in the CCRF-HSB-2 human leukemia cell line independently of the caspase-3, -8 and -9 pathways but through increased reactive oxygen species

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Tetracycline affects abnormal properties of synthetic PrP peptides and PrP(Sc) in vitro.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Removal of the N-terminal hexapeptide from human beta2-microglobulin facilitates protein aggregation and fibril formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis

28 July 2018

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

28 July 2018

1 reference

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Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model.

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Anti-amyloidogenic activity of tetracyclines: studies in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Glycosaminoglycans enhance the trifluoroethanol-induced extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Heparin strongly enhances the formation of beta2-microglobulin amyloid fibrils in the presence of type I collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Seeding-dependent propagation and maturation of amyloid fibril conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Molecular dynamics simulation suggests possible interaction patterns at early steps of beta2-microglobulin aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.178376

Patients undergoing dialysis therapy for 30 years or more survive with serious osteoarticular disorders.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023509

Altered flexibility in the substrate-binding site of related native and engineered high-alkaline Bacillus subtilisins

30 October 2018

1 reference

12 December 2020

Mechanism by which the amyloid-like fibrils of a beta 2-microglobulin fragment are induced by fluorine-substituted alcohols

1 reference

12 December 2020

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

1 reference

12 December 2020

A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.178376

1 reference

29 July 2017

1 reference

29 July 2017

1 reference