Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis (Q33748201)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20048155%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis (English)

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16 January 2020

9

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16 January 2020

author name string

Paola Bargagna-Mohan

1

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16 January 2020

Riya R Paranthan

2

1 reference

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16 January 2020

Adel Hamza

3

1 reference

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16 January 2020

Neviana Dimova

4

1 reference

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16 January 2020

Beatrice Trucchi

5

1 reference

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16 January 2020

Cidambi Srinivasan

6

1 reference

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16 January 2020

Gregory I Elliott

7

1 reference

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16 January 2020

Chang-Guo Zhan

8

1 reference

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16 January 2020

Haiyan Zhu

10

1 reference

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16 January 2020

Kousuke Kasahara

11

1 reference

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16 January 2020

Masaki Inagaki

12

1 reference

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16 January 2020

Franca Cambi

13

1 reference

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16 January 2020

Royce Mohan

14

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16 January 2020

language of work or name

English

0 references

publication date

4 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20048155%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

16 January 2020

published in

1 reference

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16 January 2020

volume

285

1 reference

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16 January 2020

issue

10

1 reference

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16 January 2020

page(s)

7657-7669

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Müller cell activation, proliferation and migration following laser injury

16 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Intermediate filaments exchange subunits along their length and elongate by end-to-end annealing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

The bright side of the glial scar in CNS repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

A dominant vimentin mutant upregulates Hsp70 and the activity of the ubiquitin-proteasome system, and causes posterior cataracts in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Abnormal reactivity of muller cells after retinal detachment in mice deficient in GFAP and vimentin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Intermediate filaments: versatile building blocks of cell structure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Forced unfolding of proteins within cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Dynamics of mutated GFAP aggregates revealed by real-time imaging of an astrocyte model of Alexander disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Intermediate filaments: from cell architecture to nanomechanics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Attenuated glial reactions and photoreceptor degeneration after retinal detachment in mice deficient in glial fibrillary acidic protein and vimentin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

GFAP and its role in Alexander disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

New therapeutic targets in atrophic age-related macular degeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Fibrosis and diseases of the eye.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

14-3-3gamma affects dynamics and integrity of glial filaments by binding to phosphorylated GFAP.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Small molecule anti-angiogenic probes of the ubiquitin proteasome pathway: potential application to choroidal neovascularization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Müller cells in the healthy and diseased retina

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Regulatory mechanisms and functions of intermediate filaments: a study using site- and phosphorylation state-specific antibodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Development of withaferin A analogs as probes of angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Plectin regulates the organization of glial fibrillary acidic protein in Alexander disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Vimentin function in lymphocyte adhesion and transcellular migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Actin microfilament aggregation induced by withaferin A is mediated by annexin II.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

The role of Müller cells in fibrocontractive retinal disorders

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Intermediate filament proteins and their associated diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Withaferin A is a potent inhibitor of angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Astrocyte intermediate filaments in CNS pathologies and regeneration.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Self-assembly of the cytoskeletal glial fibrillary acidic protein is inhibited by an isoform-specific C terminus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Specific in vivo phosphorylation sites determine the assembly dynamics of vimentin intermediate filaments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Up-regulation of glial fibrillary acidic protein in response to retinal injury: its potential role in glial remodeling and a comparison to vimentin expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Intermediate filaments are dynamic and motile elements of cellular architecture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Müller cell and neuronal remodeling in retinal detachment and reattachment and their potential consequences for visual recovery: a review and reconsideration of recent data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Protective role of phosphorylation in turnover of glial fibrillary acidic protein in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Astrocytic intermediate filaments: lessons from GFAP and vimentin knock-out mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

CD18 and ICAM-1-dependent corneal neovascularization and inflammation after limbal injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Impaired wound healing in embryonic and adult mice lacking vimentin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Molecular genetics of human retinal disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Rapid movements of vimentin on microtubule tracks: kinesin-dependent assembly of intermediate filament networks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Decreased synthesis of glycosphingolipids in cells lacking vimentin intermediate filaments.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

The function of intermediate filaments in cell shape and cytoskeletal integrity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Disrupted glial fibrillary acidic protein network in astrocytes from vimentin knockout mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Molecular profile of reactive astrocytes--implications for their role in neurologic disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Intermediate filament and related proteins: potential activators of nucleosomes during transcription initiation and elongation?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Immunohistological localization of desmin, the muscle-type 100 A filament protein, in rat astrocytes and Müller glia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Glial fibrillary acidic protein in the cytoskeletal and soluble protein fractions of the developing rat brain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Phosphorylation sites linked to glial filament disassembly in vitro locate in a non-alpha-helical head domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Involvement of the consensus sequence motif at coil 2b in the assembly and stability of vimentin filaments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Intermediate-sized filaments of human endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Under stress, the absence of intermediate filaments from Müller cells in the retina has structural and functional consequences

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Robust neural integration from retinal transplants in mice deficient in GFAP and vimentin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Control of Müller glial cell proliferation and activation following retinal injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

A quantitative kinetic model for the in vitro assembly of intermediate filaments from tetrameric vimentin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Plectin deficiency affects precursor formation and dynamics of vimentin networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Efficacy of Rho-kinase inhibition in promoting cell survival and reducing reactive gliosis in the rodent retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Identification and characterization of GFAPkappa, a novel glial fibrillary acidic protein isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Contribution of intermediate filaments to cell stiffness, stiffening, and growth.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844212

Characterization of Disulfide Crosslink Formation of Human Vimentin at the Dimer, Tetramer, and Intermediate Filament Levels

30 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.093765

Intermediate filament protein partnership in astrocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20048155

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Down-regulation of the retinoblastoma protein (rb) is associated with rat oligodendrocyte differentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20048155

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.093765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20048155%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20048155%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference