Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms (Q33752096)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426166%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms (English)

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27 January 2020

3

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27 January 2020

author name string

Joyce Besheer

series ordinal

1

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27 January 2020

Veronique Lepoutre

series ordinal

2

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publication date

1 August 2009

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Alcoholism: Clinical and Experimental Research

27 January 2020

published in

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27 January 2020

volume

33

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27 January 2020

issue

8

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27 January 2020

page(s)

1460-1468

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Riluzole and D-amphetamine interactions in humans

27 January 2020

cites work

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GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon

21 June 2018

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Neurosteroid modulators of GABA(A) receptors differentially modulate Ethanol intake patterns in male C57BL/6J mice

21 June 2018

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GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice.

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Coregulation of ethanol discrimination by the nucleus accumbens and amygdala.

21 June 2018

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Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.

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Role of glutamatergic and GABAergic systems in alcoholism

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Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat.

21 June 2018

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Effects of riluzole on electrically evoked neurotransmitter release

21 June 2018

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Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex

21 June 2018

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Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon

21 June 2018

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Effects of N-methyl-D-aspartate receptor antagonists on reinforced and nonreinforced responding for ethanol in rats.

21 June 2018

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The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions.

21 June 2018

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Riluzole, a glutamate release inhibitor, and motor behavior.

21 June 2018

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Blockade of morphine- and amphetamine-induced conditioned place preference in the rat by riluzole

21 June 2018

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Neurocircuitry targets in ethanol reward and dependence

21 June 2018

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Riluzole: a new agent for amyotrophic lateral sclerosis.

21 June 2018

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GABAA and NMDA receptor subunit mRNA expression in ethanol dependent rats.

21 June 2018

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The pharmacology and mechanism of action of riluzole

21 June 2018

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Cellular and behavioral neurobiology of alcohol: receptor-mediated neuronal processes.

21 June 2018

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The protein kinase C family for neuronal signaling

21 June 2018

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Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes

21 June 2018

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Neurotransmitter and neuromodulatory mechanisms involved in alcohol abuse and alcoholism

21 June 2018

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An animal model for testing effects of drugs on alcohol withdrawal reactions

21 June 2018

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Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats.

21 June 2018

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Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils.

21 June 2018

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Benzodiazepines in the treatment of alcoholism

21 June 2018

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Modulation of ion channel activity: a key function of the protein kinase C enzyme family.

21 June 2018

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Ethanol withdrawal seizures and the NMDA receptor complex

21 June 2018

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Management of the alcohol withdrawal syndrome

21 June 2018

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Anticonvulsant and sleep-waking influences of riluzole in a rat model of absence epilepsy.

21 June 2018

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21 June 2018

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Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia

21 June 2018

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Role of the gamma-aminobutyric acid receptor/chloride channel complex in tolerance to ethanol and cross-tolerance to diazepam and pentobarbital

21 June 2018

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Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

21 June 2018

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Anesthetic properties of riluzole (54274 RP), a new inhibitor of glutamate neurotransmission

21 June 2018

1 reference

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Ethanol Self‐Administration in Deprived Rats: Effects of Ro15‐4513 Alone, and in Combination with Flumazenil (Ro15‐1788)

21 June 2018

1 reference

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Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety

21 June 2018

1 reference

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Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice

30 October 2018

1 reference

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Baclofen-induced reduction of alcohol reinforcement in alcohol-preferring rats

30 October 2018

1 reference

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Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats

30 October 2018

1 reference

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The GABA(A) receptor alpha1 subtype in the ventral pallidum regulates alcohol-seeking behaviors.

30 October 2018

1 reference

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Neuroprotective agent riluzole potentiates postsynaptic GABA(A) receptor function

30 October 2018

1 reference

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Reduced ethanol withdrawal severity and altered withdrawal-induced c-fos expression in various brain regions of mice lacking protein kinase C-epsilon

30 October 2018

1 reference

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Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice.

30 October 2018

1 reference

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Effect of riluzole and gabapentin on cocaine- and methamphetamine-induced behavioral sensitization in mice.

30 October 2018

1 reference

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A novel neuroprotective mechanism of riluzole: direct inhibition of protein kinase C.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

GABA(A) receptors modulate ethanol-induced conditioned place preference and taste aversion in mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

Discriminative stimulus effects of glutamate release inhibitors in rats trained to discriminate ethanol.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

Effects of ventral tegmental microinjections of the GABAA agonist muscimol on self-administration of ethanol and sucrose.

30 October 2018

1 reference

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GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

Riluzole, a novel antiglutamate, blocks GABA uptake by striatal synaptosomes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

Genetic correlations with ethanol withdrawal severity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845177

2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--I. Anticonvulsant properties

30 October 2018

1 reference

12 December 2020

Riluzole decreases the abstinence syndrome and physical dependence in morphine-dependent mice

1 reference

12 December 2020

Alcohol withdrawal reactions after chronic intake of chlordiazepoxide and ethanol

1 reference

12 December 2020

Drinking patterns as predictors of alcohol withdrawal reactions in DBA/2J mice

1 reference

12 December 2020

Ethanol-like discriminative stimulus effects of non-competitive n-methyl-d-aspartate antagonists

1 reference

12 December 2020

Relationship of alcohol dose to intensity of withdrawal signs in mice

1 reference

12 December 2020

Ethanol-reinforced behaviour in the rat: effects of uncompetitive NMDA receptor antagonist, memantine

1 reference

12 December 2020

Ethanol dependence in the rat: A parametric analysis

1 reference

12 December 2020

Oral administration of glycine and polyamine receptor antagonists blocks ethanol withdrawal seizures

1 reference

12 December 2020

A comparison of the pharmacokinetics and tolerability of riluzole after repeat dose administration in healthy elderly and young volunteers

1 reference

12 December 2020

Bidirectional effects of GABAergic agonists and antagonists on maintenance of voluntary ethanol intake in rats

1 reference

12 December 2020

Diurnal variation in plasma ethanol levels of TO and CBA mice on chronic ethanol drinking or ethanol liquid diet schedules

1 reference

12 December 2020

The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1

1 reference

12 December 2020

GABAergic involvement in the acquisition of voluntary ethanol intake in laboratory rats

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12 December 2020

MK-801 potently inhibits alcohol withdrawal seizures in rats

1 reference

12 December 2020

10.1111/J.1530-0277.2009.00976.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426166%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426166%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

19426166

1 reference