Monoclonal antibody-glial-derived neurotrophic factor fusion protein penetrates the blood-brain barrier in the mouse (Q33754804)

29 July 2017

title

Monoclonal antibody-glial-derived neurotrophic factor fusion protein penetrates the blood-brain barrier in the mouse (English)

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29 July 2017

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5

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29 July 2017

2

Ruben J Boado

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29 July 2017

Qing-Hui Zhou

1

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29 July 2017

Jeff Zhiqiang Lu

series ordinal

3

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29 July 2017

Eric Ka-Wai Hui

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4

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29 July 2017

language of work or name

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14 January 2010

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Drug Metabolism and Disposition

29 July 2017

published in

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29 July 2017

volume

38

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29 July 2017

issue

4

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29 July 2017

page(s)

566-572

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Pharmacokinetics and brain uptake of a genetically engineered bifunctional fusion antibody targeting the mouse transferrin receptor

29 July 2017

cites work

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14 July 2018

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Uptake of ANG1005, a novel paclitaxel derivative, through the blood-brain barrier into brain and experimental brain metastases of breast cancer

14 July 2018

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Comparison of blood-brain barrier transport of glial-derived neurotrophic factor (GDNF) and an IgG-GDNF fusion protein in the rhesus monkey

14 July 2018

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Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse

14 July 2018

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The Structure of the Glial Cell Line-derived Neurotrophic Factor-Coreceptor Complex: INSIGHTS INTO RET SIGNALING AND HEPARIN BINDING

14 July 2018

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Altered glial cell line-derived neurotrophic factor (GDNF) concentrations in the brain of patients with depressive disorder: a comparative post-mortem study

14 July 2018

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Re-engineering biopharmaceuticals for delivery to brain with molecular Trojan horses

14 July 2018

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GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier

14 July 2018

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Point source concentration of GDNF may explain failure of phase II clinical trial

14 July 2018

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Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease

14 July 2018

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Partial deletion of glial cell line-derived neurotrophic factor (GDNF) in mice: Effects on sucrose reward and striatal GDNF concentrations

14 July 2018

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Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease.

14 July 2018

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Increased extracellular dopamine concentrations and FosB/DeltaFosB expression in striatal brain areas of heterozygous GDNF knockout mice

14 July 2018

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A rapid assay for glial cell line-derived neurotrophic factor and neurturin based on transfection of cells with tyrosine hydroxylase promoter-luciferase construct.

14 July 2018

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Glial cell line-derived neurotrophic factor does not enter normal mouse brain

14 July 2018

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14 July 2018

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Glial cell line-derived neurotrophic factor attenuates behavioural deficits and regulates nigrostriatal dopaminergic and peptidergic markers in 6-hydroxydopamine-lesioned adult rats: comparison of intraventricular and intranigral delivery

14 July 2018

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Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate

14 July 2018

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Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins

14 July 2018

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Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo

14 July 2018

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Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice

14 July 2018

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30 October 2018

Identifiers

DOI

10.1124/DMD.109.031534

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29 July 2017

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29 July 2017

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