Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2 (Q33755206)

29 July 2017

title

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2 (English)

1 reference

29 July 2017

1 reference

Kevin J French

1

1 reference

29 July 2017

Yan Zhuang

2

1 reference

29 July 2017

Lynn W Maines

3

1 reference

29 July 2017

Peng Gao

4

1 reference

29 July 2017

Wenxue Wang

5

1 reference

29 July 2017

Vladimir Beljanski

6

1 reference

29 July 2017

John J Upson

7

1 reference

29 July 2017

Cecelia L Green

8

1 reference

29 July 2017

Staci N Keller

9

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29 July 2017

Charles D Smith

10

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29 July 2017

language of work or name

English

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publication date

8 January 2010

1 reference

Journal of Pharmacology and Experimental Therapeutics

29 July 2017

published in

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29 July 2017

volume

333

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29 July 2017

issue

1

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29 July 2017

page(s)

129-139

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2846016/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy

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Sphingosine kinase-1--a potential therapeutic target in cancer.

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Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases

21 June 2018

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Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

21 June 2018

1 reference

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Sphingolipids in cancer: regulation of pathogenesis and therapy

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21 June 2018

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Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models

21 June 2018

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Sphingosine kinase 1 is up-regulated in colon carcinogenesis

21 June 2018

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Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells

21 June 2018

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SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism

21 June 2018

1 reference

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Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines

21 June 2018

1 reference

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Involvement of N-terminal-extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis

21 June 2018

1 reference

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Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846016

Role of sphingosine kinase 2 in cell migration toward epidermal growth factor

21 June 2018

1 reference

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Overexpression of sphingosine kinase 1 is an oncogenic event in erythroleukemic progression

21 June 2018

1 reference

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Regulation of sphingosine kinase 1 gene expression by protein kinase C in a human leukemia cell line, MEG-O1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846016

Development of a Syngeneic In Vivo Tumor Model and its Use in Evaluating a Novel P-Glycoprotein Modulator, PGP-4008

21 June 2018

1 reference

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Discovery and evaluation of inhibitors of human sphingosine kinase

21 June 2018

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Radiation and ceramide-induced apoptosis

21 June 2018

1 reference

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Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells

21 June 2018

1 reference

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Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

21 June 2018

1 reference

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Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells

21 June 2018

1 reference

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An oncogenic role of sphingosine kinase

21 June 2018

1 reference

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Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

21 June 2018

1 reference

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Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1.

21 June 2018

1 reference

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Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

21 June 2018

1 reference

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Molecular cloning and functional characterization of murine sphingosine kinase

21 June 2018

1 reference

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846016

Activation of casein kinase II by sphingosine.

21 June 2018

1 reference

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Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects

21 June 2018

1 reference

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Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846016

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846016

Sphingosine kinase transmits estrogen signaling in human breast cancer cells.

30 October 2018

1 reference

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Involvement of sphingosine kinase in TNF-alpha-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846016

S-15183a and b, new sphingosine kinase inhibitors, produced by a fungus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846016

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20061445

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20061445

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/JPET.109.163444

1 reference

29 July 2017

1 reference

29 July 2017

1 reference