Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands (Q33755670)

29 July 2017

title

Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands (English)

1 reference

29 July 2017

3

Jean-Louis Mergny

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29 July 2017

Laurent Lacroix

1

1 reference

29 July 2017

Aurélie Séosse

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

23 November 2010

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29 July 2017

published in

Nucleic Acids Research

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29 July 2017

volume

39

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29 July 2017

issue

4

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29 July 2017

page(s)

e21

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Creative Commons Attribution-NonCommercial 2.5 Generic

29 July 2017

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation

14 July 2018

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Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad

14 July 2018

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TERRA: telomeric repeat-containing RNA

14 July 2018

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Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands

14 July 2018

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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

14 July 2018

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G-quadruplex structures: in vivo evidence and function

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G-Quadruplex formation interferes with P1 helix formation in the RNA component of telomerase hTERC.

14 July 2018

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Mix and measure fluorescence screening for selective quadruplex binders

14 July 2018

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Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

14 July 2018

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Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

14 July 2018

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Fluorescence-based melting assays for studying quadruplex ligands

14 July 2018

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An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation

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The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells

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Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

14 July 2018

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The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides

14 July 2018

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Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA

14 July 2018

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Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase.

14 July 2018

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Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.

14 July 2018

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Analysis of a long-range interaction between conserved domains of human telomerase RNA.

14 July 2018

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Template boundary definition in mammalian telomerase

14 July 2018

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Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration

14 July 2018

1 reference

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Helix formation by guanylic acid

14 July 2018

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DNA duplex-quadruplex exchange as the basis for a nanomolecular machine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity

14 July 2018

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Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

Inhibition of telomerase by G-quartet DNA structures

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

Structure of long telomeric RNA transcripts: the G-rich RNA forms a compact repeating structure containing G-quartets

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

Structure, Interactions and Effects on Activity of the 5′-terminal Region of Human telomerase RNA

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045579

RNA quadruplex-based modulation of gene expression

30 October 2018

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12 December 2020

Dynamic roles for G4 DNA in the biology of eukaryotic cells

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12 December 2020

Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation

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12 December 2020

Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands

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12 December 2020

Inhibition of human telomerase by a G-quadruplex-interactive compound

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKQ1199

1 reference

29 July 2017

1 reference

29 July 2017

1 reference