The mitochondrial theory of aging: do damaged mitochondria accumulate by delayed degradation? (Q33756917)

29 July 2017

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title

The mitochondrial theory of aging: do damaged mitochondria accumulate by delayed degradation? (English)

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29 July 2017

Kowald A

1

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29 July 2017

1 August 1999

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29 July 2017

Experimental Gerontology

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29 July 2017

34

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29 July 2017

5

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29 July 2017

605-612

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Sequence and organization of the human mitochondrial genome

29 July 2017

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Lipid peroxidation in mitochondrial inner membranes. I. An integrative kinetic model.

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Deleterious mitochondrial DNA mutations accumulate in aging human tissues

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Decline with age of the respiratory chain activity in human skeletal muscle.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Hydroperoxide metabolism in mammalian organs

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Detection of a specific mitochondrial DNA deletion in tissues of older humans

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

A proposed refinement of the mitochondrial free radical theory of aging

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

The biologic clock: the mitochondria?

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Age-dependent increase in deleted mitochondrial DNA in the human heart: possible contributory factor to presbycardia

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Genetic toxicology of oxygen

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Quantitative allele-specific PCR: demonstration of age-associated accumulation in human tissues of the A-->G mutation at nucleotide 3243 in mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Mitochondrial role in cell aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Defects of the respiratory chain in the normal human liver and in cirrhosis during aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Do Mitochondria Produce Oxygen Radicals in vivo?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Mitochondrial DNA deletions and cytochrome c oxidase deficiency in muscle fibres

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Do mitochondrial DNA fragments promote cancer and aging?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Mitochondrial DNA mutations and neuromuscular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Ageing-associated 5 kb deletion in human liver mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

Comparison of different quantitative PCR procedures in the analysis of the 4977-bp deletion in human mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900011-X

7 January 2021

10.1016/S0531-5565(99)00011-X

Identifiers

DOI

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29 July 2017

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PubMed ID

10530786